Harber P, Lew M, Tashkin D P, Simmons M
Occupational Medicine Branch, University of California, Los Angeles 90024.
Br J Ind Med. 1987 Nov;44(11):780-4. doi: 10.1136/oem.44.11.780.
Clinical data from 624 asbestos exposed workers were analysed by factor analysis. Fifteen clinical variables were found to reflect several underlying factors: "obstruction," "interstitial disorder," "x ray change," "air tapping," and "age/exposure." Scoring individual subjects along these axes can facilitate identifying early cases and avoiding false diagnosis. The analysis suggests that screening should be multimodal and that radiographic abnormality need not imply physiological impairment.
对624名接触石棉工人的临床数据进行了因子分析。发现15个临床变量反映了几个潜在因素：“阻塞”“间质性疾病”“x光变化”“气切”和“年龄/接触情况”。沿这些轴对个体受试者进行评分有助于识别早期病例并避免误诊。该分析表明，筛查应是多模式的，且影像学异常并不一定意味着生理损伤。
