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青少年减重手术后 2-4 年的精神病理学和失调轨迹。

Trajectories of Psychopathology and Dysregulation 2-4 Years following Adolescent Bariatric Surgery.

机构信息

Division of Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Independent Scholar, Birmingham, AL, USA.

出版信息

J Pediatr Psychol. 2023 May 20;48(5):479-489. doi: 10.1093/jpepsy/jsad009.

DOI:10.1093/jpepsy/jsad009
PMID:36898044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10199728/
Abstract

OBJECTIVE

This study examined psychopathology and weight over 4 years following bariatric surgery in adolescents with obesity, as compared to a nonsurgical group. The role of psychological dysregulation in relation to psychopathology in the 2-4 year "maintenance phase" following surgery was also examined.

METHODS

Adolescent participants (122 surgical and 70 nonsurgical) completed height/weight and psychopathology assessments annually for 4 years, with dysregulation assessed at Year 2. Analyses examined the association of "High" and "Low" psychopathology with weight over time using logistic regression. Mediation analyses in the surgical group examined indirect effects of dysregulation on percent weight loss through Year 4 psychopathology.

RESULTS

There were lower odds of "High" internalizing symptoms in the surgical group versus the nonsurgical group from baseline (presurgery) to Year 4 (OR = .39; p < .001; 42.3% "High" internalizing in surgical; 66.7% in nonsurgical) and during the 2-4 year maintenance phase (OR = .35, p < .05; 35.1% "High" internalizing in surgical; 60.8% in nonsurgical). There was a significant mediation effect in the surgical group: higher dysregulation was associated with greater Year 4 internalizing symptoms (β = .41, p < .001) which in turn was associated with less Year 4 percent weight loss (β = -.27, p < .05).

CONCLUSIONS

While the surgical group was less likely to experience internalizing symptoms, internalizing psychopathology was related to less percent weight loss in this group. Internalizing symptoms mediated the relationship between dysregulation and percent weight loss in the surgical group. Postoperative mental health follow-up is needed for adolescents into young adulthood.

摘要

目的

本研究比较了肥胖青少年接受减肥手术后与未手术组 4 年内的精神病理学和体重变化,同时还研究了手术治疗后 2-4 年“维持期”心理失调与精神病理学之间的关系。

方法

青少年患者(手术组 122 人,非手术组 70 人)每年完成身高/体重和精神病理学评估,共 4 年。在第 2 年评估失调情况。采用逻辑回归分析,检查“高”和“低”精神病理学与随时间变化的体重之间的关联。手术组采用中介分析,检查失调对第 4 年精神病理学的影响通过年度体重减轻率的间接效应。

结果

与非手术组相比,手术组在基线(术前)至第 4 年(OR =.39;p <.001;手术组 42.3%“高”的内部症状;非手术组 66.7%)以及在 2-4 年维持期(OR =.35,p <.05;手术组 35.1%“高”的内部症状;非手术组 60.8%)中“高”的内部症状出现几率较低。手术组存在显著的中介效应:较高的失调与第 4 年的内化症状有关(β =.41,p <.001),进而与第 4 年的体重减轻率降低有关(β = -.27,p <.05)。

结论

尽管手术组发生内化症状的可能性较低,但内化精神病理学与该组体重减轻百分比较低有关。在手术组中,失调与体重减轻百分比之间的关系由内化症状介导。需要对青少年患者进行到青年期的术后心理健康随访。