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[心肌在中毒时的保护反应]

[Protective reaction of the myocardium in poisoning].

作者信息

Frolov V A, Mall G, Rieger P, Derks Kh, Antoni Z

出版信息

Biull Eksp Biol Med. 1987 Dec;104(12):739-41.

PMID:3689972
Abstract

Intensive synthesis of collagen-like substance was revealed in the rabbit myocardium during experimental diphtheria intoxication. It was more marked in the right ventricle 24 hours after the injection of diphtheria toxin. Since similar changes (the substance was mainly formed around blood vessels) have been observed in other cases of toxic myocardial alterations (i.e. ethanol intoxication, injection of pharmacological agents, etc.), it can be assumed that it is a standard protective reaction of the altered heart to the penetration of toxic agents from the blood into the myocardial tissue.

摘要

实验性白喉中毒时,兔心肌中出现了胶原样物质的大量合成。注射白喉毒素24小时后,右心室的这种现象更为明显。由于在其他中毒性心肌病变(如乙醇中毒、注射药理制剂等)中也观察到了类似变化(该物质主要在血管周围形成),可以推测这是心脏发生改变后对血液中有毒物质侵入心肌组织的一种标准保护性反应。

相似文献

1
[Protective reaction of the myocardium in poisoning].[心肌在中毒时的保护反应]
Biull Eksp Biol Med. 1987 Dec;104(12):739-41.
2
[Myocardial architectonic changes and cardiomyocytic apoptosis in the course of experimental diphtheria intoxication].[实验性白喉中毒过程中心肌结构变化及心肌细胞凋亡]
Arkh Patol. 2010 Mar-Apr;72(2):30-4.
3
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[Principles of reciprocal changes in the cardiomyocyte and hepatocyte lysosomal enzyme activities in experimental diphtheria intoxication in rabbits].[兔实验性白喉中毒时心肌细胞与肝细胞溶酶体酶活性的相互变化原理]
Biull Eksp Biol Med. 1991 Oct;112(10):342-3.
5
[Changes in myocardial ultrastructure in diphtheria intoxication].[白喉中毒时心肌超微结构的变化]
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7
[Changes in the activity of lysosomal enzymes and in the indices of cardiac contractile function in experimental diphtheria poisoning in rabbits].[家兔实验性白喉中毒时溶酶体酶活性及心脏收缩功能指标的变化]
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Contractile function of the heart and the state of some stages of lipid metabolism during acute diphtheritic intoxication.急性白喉中毒时心脏的收缩功能及脂质代谢某些阶段的状态
Bull Exp Biol Med. 2009 Sep;148(3):366-8. doi: 10.1007/s10517-010-0714-9.
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[Myocardial involvement in diphtheria patients (a review)].
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[Dynamics of ultrastructural changes in guinea pig cardiomyocytes in experimental diphtheria intoxication].
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