Daneshrad Justin A, Ordovas Karen, Sierra-Galan Lilia M, Hays Allison G, Mamas Mamas A, Bucciarelli-Ducci Chiara, Parwani Purvi
Department of Internal Medicine, Loma Linda University Health, Loma Linda, CA 92354, USA.
Department of Cardiothoracic Imaging, University of Washington, Seattle, WA 98195, USA.
J Clin Med. 2023 Mar 3;12(5):2017. doi: 10.3390/jcm12052017.
Myocardial infarction with Non Obstructive Coronary Arteries (MINOCA) is defined by patients presenting with signs and symptoms similar to acute myocardial infarction, but are found to have non-obstructive coronary arteries angiography. What was once considered a benign phenomenon, MINOCA has been proven to carry with it significant morbidity and worse mortality when compared to the general population. As the awareness for MINOCA has increased, guidelines have focused on this unique situation. Cardiac magnetic resonance (CMR) has proven to be an essential first step in the diagnosis of patients with suspected MINOCA. CMR has also been shown to be crucial when differentiating between MINOCA like presentations such as myocarditis, takotsubo and other forms of cardiomyopathy. The following review focuses on demographics of patients with MINOCA, their unique clinical presentation as well as the role of CMR in the evaluation of MINOCA.
非阻塞性冠状动脉心肌梗死(MINOCA)的定义是,患者出现与急性心肌梗死相似的体征和症状,但冠状动脉血管造影显示为非阻塞性。MINOCA曾被认为是一种良性现象,但与普通人群相比,已被证明其具有显著的发病率和更高的死亡率。随着对MINOCA的认识增加,指南已关注到这种特殊情况。心脏磁共振成像(CMR)已被证明是疑似MINOCA患者诊断的重要第一步。在鉴别类似MINOCA表现的疾病,如心肌炎、应激性心肌病和其他形式的心肌病时,CMR也被证明至关重要。以下综述重点关注MINOCA患者的人口统计学特征、其独特的临床表现以及CMR在MINOCA评估中的作用。