Ness T J, Jones S L, Gebhart G F
Department of Pharmacology, College of Medicine, University of Iowa, Iowa City 52242.
Brain Res. 1987 Nov 17;426(1):169-72. doi: 10.1016/0006-8993(87)90437-9.
The rat tail flick reflex is a commonly used assay of thermal nociception. Variability in the latency to respond due to the locus of tail heating was examined in spinalized (midthoracic) rats and evaluated retrospectively using data from two previously published studies. In all 3 sets of data, a significant relation was found between the proximal-distal site of heating on the tail and the latency of the tail flick reflex. Heating of the most distal sites resulted in shortest response latencies.
大鼠甩尾反射是一种常用的热痛觉测定方法。在脊髓横断(胸中部)大鼠中,研究了由于尾部加热部位不同而导致的反应潜伏期变异性,并使用两项先前发表研究的数据进行回顾性评估。在所有3组数据中,发现尾部加热的近-远部位与甩尾反射潜伏期之间存在显著关系。最远端部位加热导致最短的反应潜伏期。