• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在聚变反应堆中生产医用放射性同位素的可行性研究。

Feasibility Study to Byproduce Medical Radioisotopes in a Fusion Reactor.

机构信息

School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230000, China.

Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230000, China.

出版信息

Molecules. 2023 Feb 22;28(5):2040. doi: 10.3390/molecules28052040.

DOI:10.3390/molecules28052040
PMID:36903286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10004375/
Abstract

Currently, international nuclear fission reactors producing medical isotopes face the problem of shutdown and maintenance, decommissioning, or dismantling, while the production capacity of domestic research reactors for medical radioisotopes is inadequate, and the supply capacity for medical radioisotopes faces major challenges in the future. Fusion reactors are characterized by high neutron energy, high flux density, and the absence of highly radioactive fission fragments. Additionally, compared to fission reactors, the reactivity of the fusion reactor core is not significantly affected by the target material. By building a preliminary model of the China Fusion Engineering Test Reactor (CFETR), a Monte Carlo simulation was performed for particle transport between different target materials at a fusion power of 2 GW. The yields (specific activity) of six medical radioisotopes (C, Sr, P, Cu, Cu, and Mo) with various irradiation positions, different target materials, and different irradiation times were studied, and compared with those of other high-flux engineering test reactors (HFETR) and the China Experimental Fast Reactor (CEFR). The results show that this approach not only provides competitive medical isotope yield, but also contributes to the performance of the fusion reactor itself, e.g., tritium self-sustainability and shielding performance.

摘要

目前,生产医用同位素的国际核裂变反应堆面临着停机维护、退役或拆除的问题,而国内医用放射性同位素研究反应堆的生产能力不足,医用放射性同位素的供应能力在未来面临重大挑战。核聚变反应堆的特点是中子能量高、通量密度高,而且没有高放射性裂变碎片。此外,与裂变反应堆相比,核聚变堆芯的反应性受靶材料的影响不大。通过建立中国聚变工程试验堆(CFETR)的初步模型,对 2GW 聚变功率下不同靶材料之间的粒子输运进行了蒙特卡罗模拟。研究了六种不同辐照位置、不同靶材料和不同辐照时间的医用放射性同位素(C、Sr、P、Cu、Cu 和 Mo)的产额(比活度),并与其他高通量工程试验堆(HFETR)和中国实验快堆(CEFR)进行了比较。结果表明,这种方法不仅提供了有竞争力的医用同位素产额,而且对聚变反应堆本身的性能也有贡献,例如氚的自持性和屏蔽性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/c31039760e85/molecules-28-02040-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/d7b073476f62/molecules-28-02040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/6960543eb06c/molecules-28-02040-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/c31039760e85/molecules-28-02040-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/d7b073476f62/molecules-28-02040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/6960543eb06c/molecules-28-02040-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/591d/10004375/c31039760e85/molecules-28-02040-g003.jpg

相似文献

1
Feasibility Study to Byproduce Medical Radioisotopes in a Fusion Reactor.在聚变反应堆中生产医用放射性同位素的可行性研究。
Molecules. 2023 Feb 22;28(5):2040. doi: 10.3390/molecules28052040.
2
Fission-Produced Mo Without a Nuclear Reactor.无需核反应堆裂变产生的钼。
J Nucl Med. 2017 Mar;58(3):514-517. doi: 10.2967/jnumed.116.181040. Epub 2016 Sep 29.
3
Gold nanoparticles production using reactor and cyclotron based methods in assessment of (196,198)Au production yields by (197)Au neutron absorption for therapeutic purposes.使用基于反应堆和回旋加速器的方法生产金纳米颗粒,以评估通过(197)金的中子吸收用于治疗目的的(196,198)金的产率。
Mater Sci Eng C Mater Biol Appl. 2016 Nov 1;68:449-454. doi: 10.1016/j.msec.2016.06.018. Epub 2016 Jun 6.
4
Activation analysis of concrete and graphite in the experimental reactor RUS.俄罗斯实验反应堆中混凝土和石墨的活化分析
Radiat Prot Dosimetry. 2005;115(1-4):104-9. doi: 10.1093/rpd/nci049.
5
Hardening neutron spectrum for advanced actinide transmutation experiments in the ATR.用于先进锕系元素嬗变实验的ATR中的硬化中子能谱。
Radiat Prot Dosimetry. 2005;115(1-4):63-8. doi: 10.1093/rpd/nci167.
6
Future development of global molybdenum-99 production and saving of atmospheric radioxenon emissions by using nuclear fusion-based approaches.利用基于核聚变的方法实现全球钼-99生产的未来发展以及减少大气放射性氙排放。
J Environ Radioact. 2022 Dec;255:107049. doi: 10.1016/j.jenvrad.2022.107049. Epub 2022 Oct 21.
7
Characterization of the fast neutron irradiation facility of the Portuguese Research Reactor after core conversion.葡萄牙研究堆堆芯转换后快中子辐照设施的特性描述
Appl Radiat Isot. 2011 Aug;69(8):1128-30. doi: 10.1016/j.apradiso.2010.10.016. Epub 2010 Oct 27.
8
Numerical and experimental determination of neutron characteristics in irradiation rigs operated in LVR-15 research reactor.
Radiat Prot Dosimetry. 2014 Oct;161(1-4):316-20. doi: 10.1093/rpd/ncu196. Epub 2014 Jun 27.
9
Optimization design research for 89Sr production in China Experimental Fast Reactor.
Appl Radiat Isot. 2018 Jul;137:167-171. doi: 10.1016/j.apradiso.2018.03.020. Epub 2018 Mar 28.
10
Dosimetry at the Portuguese research reactor using thermoluminescence measurements and Monte Carlo calculations.葡萄牙研究堆的剂量测定:采用热释光测量和蒙特卡罗计算方法
Radiat Prot Dosimetry. 2006;120(1-4):349-53. doi: 10.1093/rpd/nci560. Epub 2006 May 15.

本文引用的文献

1
Systematic Review and Meta-Analysis on the Sensitivity and Specificity of C/C-Urea Breath Tests in the Diagnosis of Infection.碳-13/碳-14尿素呼气试验诊断感染的敏感性和特异性的系统评价与Meta分析
Diagnostics (Basel). 2022 Oct 7;12(10):2428. doi: 10.3390/diagnostics12102428.
2
Cu Production Capabilities: A Mini Review.铜的生产能力:小型综述。
Molecules. 2022 Feb 23;27(5):1501. doi: 10.3390/molecules27051501.
3
Current status and future perspective of radiopharmaceuticals in China.中国放射性药物的现状和未来展望。
Eur J Nucl Med Mol Imaging. 2022 Jul;49(8):2514-2530. doi: 10.1007/s00259-021-05615-6. Epub 2021 Nov 12.
4
Practicality of hierarchically macro/mesoporous γ-AlO as a promising sorbent in the preparation of low specific activity Mo/Tc generator.层状大/介孔 γ-AlO 作为一种很有前途的吸附剂,用于制备低比活度 Mo/Tc 发生器的实用性。
Appl Radiat Isot. 2021 Dec;178:109986. doi: 10.1016/j.apradiso.2021.109986. Epub 2021 Oct 16.
5
Smaller and quicker with spherical tokamaks and high-temperature superconductors.采用球形托卡马克和高温超导体会更小更快。
Philos Trans A Math Phys Eng Sci. 2019 Mar 25;377(2141):20170438. doi: 10.1098/rsta.2017.0438.
6
Targeted Radionuclide Therapy of Painful Bone Metastases: Past Developments, Current Status, Recent Advances and Future Directions.靶向放射性核素治疗骨转移疼痛:过去的发展、现状、最新进展和未来方向。
Curr Med Chem. 2020;27(19):3187-3249. doi: 10.2174/0929867326666190201142814.
7
Simultaneous production of high specific activity 64Cu and 61Co with 11.4 MeV protons on enriched 64Ni nuclei.用11.4兆电子伏质子轰击富集的64镍核同时产生高比活度的64铜和61钴。
Appl Radiat Isot. 2007 Oct;65(10):1115-20. doi: 10.1016/j.apradiso.2007.05.012. Epub 2007 Jul 3.
8
Bone pain palliation with strontium-89 in cancer patients with bone metastases.锶-89对癌症骨转移患者的骨痛缓解作用
Q J Nucl Med. 2001 Mar;45(1):78-83.