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清醒状态下激光消融术联合治疗脑肿瘤和癫痫时的连续神经心理学测试。

Awake Laser Ablation with Continuous Neuropsychological Testing During Treatment of Brain Tumors and Epilepsy.

机构信息

Department of Neurosurgery, Rigshospitalet, Entrance 8, 6th Floor, Inge Lehmanns Vej 8, 2100, Copenhagen East, Denmark.

Center for Neurorehabilitation, Lions Kollegiet, Copenhagen, Denmark.

出版信息

Neurosurg Clin N Am. 2023 Apr;34(2):239-245. doi: 10.1016/j.nec.2022.11.003. Epub 2023 Jan 31.

Abstract

MR-guided laser interstitial thermal therapy (LITT) is feasible and safe in the awake patient. Awake LITT may be performed with analgesics for head fixation in a head-ring, no sedation during laser ablation, and with continuous neurological testing in patients with brain tumors and epilepsy. In the LITT treatment of lesions near eloquent areas and subcortical fiber tracts, neurological function can potentially be preserved by monitoring the patient during laser ablation.

摘要

磁共振引导下激光间质热疗(LITT)在清醒患者中是可行且安全的。对于脑肿瘤和癫痫患者,清醒 LITT 可在头环固定头部时使用镇痛药,激光消融时无需镇静,并进行连续神经功能测试。在靠近语言功能区和皮质下纤维束的病变的 LITT 治疗中,通过在激光消融过程中监测患者,可以潜在地保留神经功能。

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