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一项不寻常的发现:松果体区乳头状肿瘤。

An Unusual Finding: Papillary Tumor of the Pineal Region.

作者信息

Kennedy Grace, Degueure Arielle, Dai Min, Cuevas-Ocampo Areli, Arevalo Octavio

机构信息

Radiology, Louisiana State University Health Shreveport, Shreveport, USA.

Pathology, Louisiana State University Health Shreveport, Shreveport, USA.

出版信息

Cureus. 2023 Feb 7;15(2):e34725. doi: 10.7759/cureus.34725. eCollection 2023 Feb.

DOI:10.7759/cureus.34725
PMID:36909052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9997103/
Abstract

A papillary tumor of the pineal region (PTPR) is a rare tumor of neuroepithelial origin formed from specialized ependymocytes of the subcommissural organ located in the lining of the posterior commissure, not the pineal gland itself. Patients with this type of tumor generally present with nonspecific symptoms secondary to obstructive hydrocephalus such as headache and vision changes. The mean age of patient presentation is 31, with a slight predominance in females. This type of tumor has a high rate of recurrence (56%) following surgical resection. This case study describes the presentation of this uncommon tumor in a 61-year-old woman, including presentation, imaging, surgery, and pathology findings.

摘要

松果体区乳头状瘤(PTPR)是一种罕见的神经上皮起源肿瘤,由位于后连合内衬的连合下器官的特殊室管膜细胞形成,而非松果体本身。这类肿瘤患者通常因梗阻性脑积水出现非特异性症状,如头痛和视力改变。患者出现症状的平均年龄为31岁,女性略占多数。这类肿瘤手术切除后复发率较高(56%)。本病例研究描述了一名61岁女性中这种罕见肿瘤的表现,包括临床表现、影像学、手术及病理结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/17f38955ecea/cureus-0015-00000034725-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/5c658cf505ae/cureus-0015-00000034725-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/17acd4ac3375/cureus-0015-00000034725-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/17f38955ecea/cureus-0015-00000034725-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/5c658cf505ae/cureus-0015-00000034725-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/17acd4ac3375/cureus-0015-00000034725-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cf/9997103/17f38955ecea/cureus-0015-00000034725-i03.jpg

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本文引用的文献

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Asian J Neurosurg. 2021 May 28;16(2):398-401. doi: 10.4103/ajns.AJNS_439_20. eCollection 2021 Apr-Jun.
2
PTEN R130Q Papillary Tumor of the Pineal Region (PTPR) with Chromosome 10 Loss Successfully Treated with Everolimus: A Case Report.PTEN R130Q 松果体区乳头状肿瘤(PTPR)伴 10 号染色体缺失,依维莫司治疗有效:一例报告。
Curr Oncol. 2021 Mar 20;28(2):1274-1279. doi: 10.3390/curroncol28020121.
3
Papillary Tumor of the Pineal Region: A Distinct Molecular Entity.
松果体区乳头状肿瘤:一种独特的分子实体。
Brain Pathol. 2016 Mar;26(2):199-205. doi: 10.1111/bpa.12282. Epub 2015 Jul 30.
4
Cellular pleomorphism in papillary tumors of the pineal region.松果体区乳头状肿瘤的细胞多形性。
Brain Tumor Pathol. 2013 Apr;30(2):93-8. doi: 10.1007/s10014-012-0103-3. Epub 2012 May 24.
5
Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary: new tumor entities in the 2007 WHO Classification.松果体区乳头状肿瘤和垂体梭形细胞嗜酸细胞瘤:2007年世界卫生组织分类中的新肿瘤实体。
Brain Pathol. 2007 Jul;17(3):314-8. doi: 10.1111/j.1750-3639.2007.00081.x.
6
Papillary tumor of the pineal region.松果体区乳头状肿瘤。
Am J Surg Pathol. 2003 Apr;27(4):505-12. doi: 10.1097/00000478-200304000-00011.