Pratap R C
Department of Medicine, University Hospital (USM), Kubang Kerian, Kelantan, Malaysia.
Clin Neurol Neurosurg. 1987;89(4):237-42. doi: 10.1016/s0303-8467(87)80022-7.
The present study deals with observations on the "speech evoked potential"-a late positive potential evoked by word repetition. These potentials, evoked by "silent" repetition of polysyllabic words, were averaged and recorded from the scalp overlying the inferior frontal regions on both sides in 20 normal healthy subjects of ages ranging from 13-58 years. The potential had a triphasic negative, positive, negative morphology and was present over both hemispheres in left as well as right handed subjects. The main positive deflection and mean latencies of 219.2 msec and 221.6 msec and mean amplitude of 6.2 muv and 6.5 muv respectively on the left and right sides. Though there were interindividual variations in latency, amplitude and morphology, there was a high degree of intraindividual similarity and reproducibility in subjects. The variations in these parameters with age, sex and handedness are discussed. In 10 patients with cerebral lesions, the evoked potential was normal in 5 cases with right frontal lesions and showed abnormalities in 3 of 5 cases with left frontal lesions. The speech evoked potential may be useful in the further study of electrical correlates of speech output in speech disorders.
本研究涉及对“言语诱发电位”的观察——一种由单词重复诱发的晚期正电位。这些电位由多音节词的“默读”重复诱发，在年龄为13至58岁的20名正常健康受试者双侧额下回上方头皮记录并平均。该电位具有三相负、正、负形态，在左利手和右利手受试者的双侧半球均有出现。左侧和右侧的主要正波偏转、平均潜伏期分别为219.2毫秒和221.6毫秒，平均波幅分别为6.2微伏和6.5微伏。尽管潜伏期、波幅和形态存在个体间差异，但受试者个体内具有高度相似性和可重复性。讨论了这些参数随年龄、性别和利手的变化。在10例脑损伤患者中，5例右侧额叶损伤患者的诱发电位正常，5例左侧额叶损伤患者中有3例出现异常。言语诱发电位可能有助于进一步研究言语障碍中言语输出的电相关性。
