Makepeace A R, Fermont D C, Bennett M H
Meyerstein Institute of Radiotherapy and Oncology, Middlesex Hospital, London.
Clin Radiol. 1987 Nov;38(6):609-14. doi: 10.1016/s0009-9260(87)80337-9.
Seventy-two patients with gastrointestinal non-Hodgkin's lymphoma treated between 1952 and 1980 are reviewed. The small intestine was involved in 49% of cases and the stomach in 29%. Surgical resection of the tumour was performed whenever feasible. Radiotherapy was used either adjuvantly or for incompletely excised tumours and chemotherapy was more often reserved for advanced, unresected disease. The overall 5 year survival was 36% and the 5 year relapse free survival was 22%. Forty-one (57%) patients relapsed of whom 33 (80%) subsequently died of non-Hodgkin's lymphoma. The histology in each case was reviewed using the British National Lymphoma Investigation criteria and 94% of cases were reclassified as Grade 2 non-Hodgkin's lymphoma.
对1952年至1980年间接受治疗的72例胃肠道非霍奇金淋巴瘤患者进行了回顾性研究。49%的病例累及小肠，29%累及胃。只要可行，均对肿瘤进行了手术切除。放疗用于辅助治疗或不完全切除的肿瘤，化疗更多用于晚期未切除疾病。总体5年生存率为36%，5年无复发生存率为22%。41例（57%）患者复发，其中33例（80%）随后死于非霍奇金淋巴瘤。根据英国国家淋巴瘤调查标准对每例病例的组织学进行了复查，94%的病例重新分类为2级非霍奇金淋巴瘤。
