van Zeller Cristiano, Brown Richard, Cheng Michael, Meurling Johan, McGowan Barbara, Steier Joerg
Lane Fox Respiratory Unit/Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Department of Endocrinology and Diabetes, Guy's and St Thomas' NHS Foundation Trust, London, UK.
J Thorac Dis. 2023 Feb 28;15(2):802-811. doi: 10.21037/jtd-22-1501. Epub 2023 Feb 9.
The prevalence of obstructive sleep apnoea (OSA) is increasing worldwide. Bariatric surgery is an option where conventional measures to achieve weight loss fail. We compared peri-operative outcomes in patients living with obesity with and without OSA undergoing bariatric surgery.
Retrospective cohort study of consecutive patients undergoing bariatric surgery at a tertiary referral centre. Data were extracted from electronic patient records. Primary outcomes were the rate of peri-operative complications and level of respiratory support. Secondary outcomes were length of stay (LOS), and the highest level of care required.
A total of 302 patients underwent surgery [age 47 (±11.6) years, 238 (78.8%) female, body mass index (BMI) 48.1 (±7.8) kg/m]. A total of 101 (33.4%) patients had moderate or severe OSA, or mild OSA with significant sleepiness, and were prescribed continuous positive airway pressure (CPAP), whilst 201 (66.6%) had mild OSA without symptoms or no OSA and weren't. Patients requiring CPAP were more obese (BMI 50.2 47.0 kg/m, P=0.002). Complications were analysed individually and according to the Clavien-Dindo classification. The incidence of each individual complication did not differ between groups. When grouped into Clavien-Dindo grades, only grade I complications differed: CPAP 9% non-CPAP 2.6%, P=0.02). LOS was longer in the CPAP group [3 (1.5) 2 (1.0) days, P=0.002].
The rate of peri-operative complications in patients with OSA undergoing bariatric surgery is low and can be addressed by the provision of CPAP therapy in most cases. However, a longer LOS and more frequent Grade I complications requires selection of appropriate post-operative monitoring.
阻塞性睡眠呼吸暂停(OSA)在全球的患病率正在上升。减肥手术是常规减肥措施失败后的一种选择。我们比较了接受减肥手术的肥胖患者中有无OSA的围手术期结局。
对一家三级转诊中心连续接受减肥手术的患者进行回顾性队列研究。数据从电子病历中提取。主要结局是围手术期并发症发生率和呼吸支持水平。次要结局是住院时间(LOS)和所需的最高护理级别。
共有302例患者接受了手术[年龄47(±11.6)岁,女性238例(78.8%),体重指数(BMI)48.1(±7.8)kg/m²]。共有101例(33.4%)患者患有中度或重度OSA,或伴有明显嗜睡的轻度OSA,并接受持续气道正压通气(CPAP)治疗,而201例(66.6%)患者患有无症状的轻度OSA或无OSA且未接受治疗。需要CPAP治疗的患者更肥胖(BMI 50.2对47.0 kg/m²,P=0.002)。对并发症进行了单独分析,并根据Clavien-Dindo分类进行分析。各组之间每种单独并发症的发生率没有差异。当分为Clavien-Dindo等级时,只有I级并发症有所不同:CPAP组为9%,非CPAP组为2.6%,P=0.02)。CPAP组的住院时间更长[3(1.5)天对2(1.0)天,P=0.002]。
接受减肥手术的OSA患者围手术期并发症发生率较低,在大多数情况下可通过提供CPAP治疗来解决。然而,更长的住院时间和更频繁的I级并发症需要选择合适的术后监测。