Suppr超能文献

肥胖症手术治疗阻塞性睡眠呼吸暂停的围手术期结局:一项单中心队列研究。

Peri-operative outcomes of bariatric surgery in obstructive sleep apnoea: a single-centre cohort study.

作者信息

van Zeller Cristiano, Brown Richard, Cheng Michael, Meurling Johan, McGowan Barbara, Steier Joerg

机构信息

Lane Fox Respiratory Unit/Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Department of Endocrinology and Diabetes, Guy's and St Thomas' NHS Foundation Trust, London, UK.

出版信息

J Thorac Dis. 2023 Feb 28;15(2):802-811. doi: 10.21037/jtd-22-1501. Epub 2023 Feb 9.

Abstract

BACKGROUND

The prevalence of obstructive sleep apnoea (OSA) is increasing worldwide. Bariatric surgery is an option where conventional measures to achieve weight loss fail. We compared peri-operative outcomes in patients living with obesity with and without OSA undergoing bariatric surgery.

METHODS

Retrospective cohort study of consecutive patients undergoing bariatric surgery at a tertiary referral centre. Data were extracted from electronic patient records. Primary outcomes were the rate of peri-operative complications and level of respiratory support. Secondary outcomes were length of stay (LOS), and the highest level of care required.

RESULTS

A total of 302 patients underwent surgery [age 47 (±11.6) years, 238 (78.8%) female, body mass index (BMI) 48.1 (±7.8) kg/m]. A total of 101 (33.4%) patients had moderate or severe OSA, or mild OSA with significant sleepiness, and were prescribed continuous positive airway pressure (CPAP), whilst 201 (66.6%) had mild OSA without symptoms or no OSA and weren't. Patients requiring CPAP were more obese (BMI 50.2 47.0 kg/m, P=0.002). Complications were analysed individually and according to the Clavien-Dindo classification. The incidence of each individual complication did not differ between groups. When grouped into Clavien-Dindo grades, only grade I complications differed: CPAP 9% non-CPAP 2.6%, P=0.02). LOS was longer in the CPAP group [3 (1.5) 2 (1.0) days, P=0.002].

CONCLUSIONS

The rate of peri-operative complications in patients with OSA undergoing bariatric surgery is low and can be addressed by the provision of CPAP therapy in most cases. However, a longer LOS and more frequent Grade I complications requires selection of appropriate post-operative monitoring.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)在全球的患病率正在上升。减肥手术是常规减肥措施失败后的一种选择。我们比较了接受减肥手术的肥胖患者中有无OSA的围手术期结局。

方法

对一家三级转诊中心连续接受减肥手术的患者进行回顾性队列研究。数据从电子病历中提取。主要结局是围手术期并发症发生率和呼吸支持水平。次要结局是住院时间(LOS)和所需的最高护理级别。

结果

共有302例患者接受了手术[年龄47(±11.6)岁,女性238例(78.8%),体重指数(BMI)48.1(±7.8)kg/m²]。共有101例(33.4%)患者患有中度或重度OSA,或伴有明显嗜睡的轻度OSA,并接受持续气道正压通气(CPAP)治疗,而201例(66.6%)患者患有无症状的轻度OSA或无OSA且未接受治疗。需要CPAP治疗的患者更肥胖(BMI 50.2对47.0 kg/m²,P=0.002)。对并发症进行了单独分析,并根据Clavien-Dindo分类进行分析。各组之间每种单独并发症的发生率没有差异。当分为Clavien-Dindo等级时,只有I级并发症有所不同:CPAP组为9%,非CPAP组为2.6%,P=0.02)。CPAP组的住院时间更长[3(1.5)天对2(1.0)天,P=0.002]。

结论

接受减肥手术的OSA患者围手术期并发症发生率较低,在大多数情况下可通过提供CPAP治疗来解决。然而,更长的住院时间和更频繁的I级并发症需要选择合适的术后监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/546c/9992619/2cc5d2d310a4/jtd-15-02-802-vid1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验