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一种用于缺血性中肠扭转的肠系膜上动脉按摩联合全身纤维蛋白溶解疗法的新技术:作为一种挽救生命的最后应急措施。

A Novel Technique of SMA Massage with Systemic Fibrinolytic Therapy in Ischemic Midgut Volvulus: As a Lifesaving Last Expedient.

作者信息

Giriradder Vandana Basappa, Jadhav Vinay, Anilkumar P L, Babu M Narendra

机构信息

Department of Pediatric Surgery, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India.

Department of Pediatric Surgery, Sakra World Hospital, Bengaluru, Karnataka, India.

出版信息

J Indian Assoc Pediatr Surg. 2023 Jan-Feb;28(1):25-28. doi: 10.4103/jiaps.jiaps_69_22. Epub 2022 Dec 12.

DOI:10.4103/jiaps.jiaps_69_22
PMID:36910297
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9997583/
Abstract

PURPOSE

Midgut volvulus is a surgical emergency requiring immediate intervention. Intestinal ischemia of the midgut as a consequence of volvulus from malrotation is a fateful event with high mortality and significant morbidity even in survivors. Derotation followed by correction of malrotation is the procedure of choice though has significant morbidity if intestinal reperfusion was not successful. A combined treatment to restore intestinal perfusion based on the digital massage of the superior mesenteric artery after derotation and systemic infusion of fibrinolytic has been previously reported with success but underused. Here, we report three such cases of midgut malrotation with severe intestinal ischemia due to volvulus.

MATERIALS AND METHODS

A retrospective analysis of three confirmed cases of midgut malrotation with volvulus managed with emergency laparotomy, derotation, and Superior Mesenteric Artery (SMA) massage with systemic fibrinolytic therapy, followed by correction of malrotation was evaluated.

RESULTS

There was dramatic improvement in intestinal perfusion noted in all three patients inspite of delayed presentation. 2 out of 3 patients on follow up are doing well with adequate weight gain while 1 patient succumbed due to sepsis.

CONCLUSION

Critical intestinal ischemia due to mesenteric thrombosis can persist after derotation of midgut volvulus and can lead to devastating consequences. The use of digital massage of SMA to disrupt the thrombus along with fibrinolytic therapy though reported is underutilized. Hence, awareness of this management and usage needs to be re-emphasized.

摘要

目的

中肠扭转是一种需要立即干预的外科急症。由于旋转不良导致的中肠扭转引起的肠缺血是一个致命事件,即使在幸存者中也具有高死亡率和显著的发病率。扭转复位后纠正旋转不良是首选的手术方法,但如果肠再灌注不成功,则发病率很高。先前有报道称,在扭转复位后基于肠系膜上动脉的手法按摩和全身输注纤溶药物的联合治疗可成功恢复肠灌注,但该方法未得到充分应用。在此,我们报告3例因扭转导致严重肠缺血的中肠旋转不良病例。

材料与方法

对3例确诊的中肠旋转不良伴扭转病例进行回顾性分析,这些病例均接受了急诊剖腹手术、扭转复位、肠系膜上动脉(SMA)按摩及全身纤溶治疗,随后纠正旋转不良。

结果

尽管就诊延迟,但所有3例患者的肠灌注均有显著改善。3例患者中有2例在随访中情况良好,体重增加充足,而1例患者因败血症死亡。

结论

中肠扭转复位后,肠系膜血栓形成导致的严重肠缺血可能持续存在,并可能导致灾难性后果。尽管有报道称使用SMA手法按摩来溶解血栓并联合纤溶治疗,但该方法未得到充分利用。因此,需要再次强调对这种治疗方法的认识和应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/63c6d431fa59/JIAPS-28-21-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/9b0092c38391/JIAPS-28-21-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/b1c59caada2e/JIAPS-28-21-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/63c6d431fa59/JIAPS-28-21-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/9b0092c38391/JIAPS-28-21-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/b1c59caada2e/JIAPS-28-21-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/9997583/63c6d431fa59/JIAPS-28-21-g003.jpg

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