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原发性甲状腺腺样囊性癌的放射治疗

Radiotherapy for primary thyroid adenoid cystic carcinoma.

作者信息

Duan Xiaoyu, Hu Tingting, Cai Hongyi, Lin Lili, Zeng Lu, Wang Huixia, Cao Lei, Li Xuxia

机构信息

The First Clinical Medical College, Gansu University of Chinese Medicine, Number 35 Ding Xing East Road, Lanzhou, 730000 China.

Department of Radiotherapy, Gansu Provincial Hospital, Number 204 Dong Gang West Road, Lanzhou, 730000 China.

出版信息

Open Life Sci. 2023 Mar 7;18(1):20220547. doi: 10.1515/biol-2022-0547. eCollection 2023.

Abstract

Primary thyroid adenoid cystic carcinoma (PTACC) is an extremely rare type of mucin-secreting adenocarcinoma. Currently, it is difficult to diagnose, and it lacks standard treatment protocols. We report the case of a 53-year-old female patient with PTACC who underwent additional intensity-modulated radiotherapy 1 month after surgical treatment with an uneventful course. No invasion or distant metastasis was detected at the 7-month follow-up after radiotherapy, and the prognosis was favorable. In this case, herein, we have summarized the diagnostic features of the disease and proposed that postoperative adjuvant radiotherapy can significantly improve the patient's prognosis. Finally, we further confirmed the important role of radiotherapy in PTACC by reviewing relevant literature, which may provide clinicians with valuable treatment experience.

摘要

原发性甲状腺腺样囊性癌(PTACC)是一种极其罕见的黏液分泌性腺癌。目前,其诊断困难,且缺乏标准治疗方案。我们报告了一例53岁患有PTACC的女性患者,该患者在手术治疗1个月后接受了调强放疗,过程顺利。放疗后7个月的随访中未发现侵袭或远处转移,预后良好。在此病例中,我们总结了该疾病的诊断特征,并提出术后辅助放疗可显著改善患者预后。最后,我们通过回顾相关文献进一步证实了放疗在PTACC中的重要作用,这可能为临床医生提供有价值的治疗经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c912/9993328/6c3f0c3baaca/j_biol-2022-0547-fig001.jpg

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