单细胞血红蛋白（血红素-SCP）具有益生元潜力，可在小型宠物犬中建立健康的肠道微生物群。
Single-cell hemoprotein (heme-SCP) exerts the prebiotic potential to establish a healthy gut microbiota in small pet dogs.
作者信息
Lee Seungki, Choi Ahyoung, Park Kyung-Hoon, Lee Seoyeon, Yoon Hyunjin, Kim Pil
机构信息
Department of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon, Gyeonggi 14662 South Korea.
HemoLab Ltd. Co., Bucheon, 14622 South Korea.
出版信息
Food Sci Biotechnol. 2022 Nov 23;32(4):489-496. doi: 10.1007/s10068-022-01195-9. eCollection 2023 Mar.
UNLABELLED
To investigate the effect of the single-cell hemoprotein (heme-SCP) source on animals, a dog-treat (100 g for each dog) harboring 0.2% heme-SCP was manufactured and fed to seven pet dogs (< 10 kg) in a randomized manner (irrespective of owner's feeding style, dogs' health conditions, and staple diets), and the feces before and after the dog-treat diet were analyzed to define the structure of the microbiota. The total bacterial species of the seven dogs showed no difference (564-584), although the bacterial compositions varied significantly. The Firmicutes phylum increased (54.7-73.7%), showing differential species composition before and after heme-SCP intake. Proteobacteria, Bacteroidetes, and Fusobacteria decreased (5.4-3.8%, 32.9-16.8%, and 6.3-3.6%, respectively), which agreed with the previous observation of deliberate feeding. Therefore, it is conceivable that heme-SCP as a prebiotic can shape the gut microbiota regardless of the administration method.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s10068-022-01195-9.
未标注
为研究单细胞血红蛋白（血红素 - SCP）来源对动物的影响，制备了含有0.2%血红素 - SCP的犬粮（每只犬100克），并以随机方式喂给7只宠物犬（体重<10千克）（不考虑主人的喂食方式、犬的健康状况和主要饮食），分析犬粮饮食前后的粪便以确定微生物群的结构。7只犬的细菌总数没有差异（564 - 584），尽管细菌组成有显著变化。厚壁菌门增加（54.7% - 73.7%），显示血红素 - SCP摄入前后物种组成不同。变形菌门、拟杆菌门和梭杆菌门减少（分别为5.4% - 3.8%、32.9% - 16.8%和6.3% - 3.6%），这与之前有意喂食的观察结果一致。因此，可以想象血红素 - SCP作为益生元可以塑造肠道微生物群，而与给药方式无关。
补充信息
在线版本包含可在10.1007/s10068 - 022 - 01195 - 9获取的补充材料。
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