基线右心室功能对心脏再同步治疗反应的影响 - 一项荟萃分析。
Impact of baseline right ventricular function on the response to cardiac resynchronization therapy - A meta-analysis.
机构信息
Department of Cardiology, Georgios Papanikolaou General Hospital, Leoforos Papanikolaou, Pylaia, Thessaloniki, PK 57010, Greece.
3(rd) Cardiology Department, Hippokration General Hospital, Aristotle University Medical School, Κonstantinoupoleos 49, Thessaloniki, PK 54642, Greece.
出版信息
Hellenic J Cardiol. 2023 Sep-Oct;73:61-68. doi: 10.1016/j.hjc.2023.03.002. Epub 2023 Mar 11.
Baseline right ventricular (RV) function potentially determines the response to Cardiac Resynchronization Therapy (CRT) but is not included in the current selection criteria. In this meta-analysis, we examined the value of echocardiographic indices of RV function as potential predictors of CRT outcomes in patients with standard indications for CRT. Baseline tricuspid annular plane systolic excursion was consistently higher in CRT responders, and this association appears independent of age, sex, ischemic etiology of heart failure, and baseline left ventricular ejection fraction. This proof-of-concept meta-analysis of observational data may justify a more detailed assessment of RV function as an additional component in the selection process of CRT candidates.
基线右心室（RV）功能可能决定了心脏再同步治疗（CRT）的反应，但目前的选择标准并未包括这一因素。在这项荟萃分析中，我们研究了 RV 功能的超声心动图指数作为 CRT 适应证患者 CRT 结局潜在预测因子的价值。CRT 反应者的基线三尖瓣环平面收缩期位移始终较高，这种相关性似乎独立于年龄、性别、心力衰竭的缺血病因和基线左心室射血分数。这项观察性数据的概念验证性荟萃分析可能证明更详细地评估 RV 功能作为 CRT 候选者选择过程中的附加组件是合理的。
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