Division of Surgical Oncology, Department of Surgery, Rutgers New Jersey Medical School, Newark, NJ. Electronic address: https://twitter.com/ad_singh09.
Division of Surgical Oncology, Department of Surgery, Rutgers New Jersey Medical School, Newark, NJ. Electronic address: https://twitter.com/NealPanse.
Surgery. 2023 Jun;173(6):1323-1328. doi: 10.1016/j.surg.2023.01.017. Epub 2023 Mar 11.
Laparoscopic cholecystectomy is the current standard of care treatment for benign gallbladder disease. Robotic cholecystectomy is another approach for performing cholecystectomy that offers a surgeon better dexterity and visualization. However, robotic cholecystectomy may increase cost without sufficient evidence to suggest an improvement in clinical outcomes. The purpose of this study was to construct a decision tree model to compare cost-effectiveness of laparoscopic cholecystectomy and robotic cholecystectomy.
Complication rates and effectiveness associated with robotic cholecystectomy and laparoscopic cholecystectomy over a 1-year time frame were compared using a decision tree model populated with data from the published literature. Cost was calculated using Medicare data. Effectiveness was represented by quality-adjusted life-years. The primary outcome of the study was incremental cost-effectiveness ratio, which compares the cost per quality-adjusted life-year of the 2 interventions. The willingness-to-pay threshold was set at $100,000/quality-adjusted life-year. Results were confirmed with 1-way, 2-way, and probabilistic sensitivity analyses varying branch-point probabilities.
The studies used in our analysis included 3,498 patients who underwent laparoscopic cholecystectomy, 1,833 patients who underwent robotic cholecystectomy, and 392 patients who required conversion to open cholecystectomy. Laparoscopic cholecystectomy produced 0.9722 quality-adjusted life-years, costing $9,370.06. Robotic cholecystectomy produced an additional 0.0017 quality-adjusted life-years at an additional $3,013.64. These results equate to an incremental cost-effectiveness ratio of $1,795,735.21/quality-adjusted life-year. This exceeds the willingness-to-pay threshold, making laparoscopic cholecystectomy the more cost-effective strategy. Sensitivity analyses did not alter results.
Traditional laparoscopic cholecystectomy is the more cost-effective treatment modality for benign gallbladder disease. At present, robotic cholecystectomy is not able to improve clinical outcomes enough to justify its added cost.
腹腔镜胆囊切除术是治疗良性胆囊疾病的当前标准治疗方法。机器人胆囊切除术是另一种进行胆囊切除术的方法,它为外科医生提供了更好的灵活性和可视化效果。然而,机器人胆囊切除术可能会增加成本,而没有足够的证据表明其在临床结果方面有所改善。本研究的目的是构建一个决策树模型,以比较腹腔镜胆囊切除术和机器人胆囊切除术的成本效益。
使用决策树模型比较了在 1 年时间内与机器人胆囊切除术和腹腔镜胆囊切除术相关的并发症发生率和有效性,该模型使用了来自已发表文献的数据进行填充。成本使用医疗保险数据进行计算。有效性用质量调整生命年来表示。该研究的主要结果是增量成本效益比,它比较了两种干预措施的每质量调整生命年的成本。支付意愿阈值设定为 100,000 美元/质量调整生命年。通过对分支点概率进行 1 路、2 路和概率敏感性分析,确认了结果。
我们分析中使用的研究包括 3498 例接受腹腔镜胆囊切除术的患者、1833 例接受机器人胆囊切除术的患者和 392 例需要转为开腹胆囊切除术的患者。腹腔镜胆囊切除术产生 0.9722 个质量调整生命年,成本为 9370.06 美元。机器人胆囊切除术额外产生了 0.0017 个质量调整生命年,成本增加了 3013.64 美元。这些结果相当于增量成本效益比为 17957352.1 美元/质量调整生命年。这超过了支付意愿阈值,使腹腔镜胆囊切除术成为更具成本效益的策略。敏感性分析并未改变结果。
传统的腹腔镜胆囊切除术是治疗良性胆囊疾病更具成本效益的治疗方式。目前,机器人胆囊切除术在改善临床结果方面还不足以证明其增加的成本是合理的。