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Effects and possible mechanisms of dexmedetomidine on post-operative cognitive dysfunction.

作者信息

He Huijuan, Zhu Manhua, Lyu Yupeng, Yuan Yuan, Qi Yong

机构信息

Department of Anesthesiology, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang 315000, China.

Department of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang 315000, China.

出版信息

Chin Med J (Engl). 2023 Oct 5;136(19):2392-2394. doi: 10.1097/CM9.0000000000002372.

DOI:10.1097/CM9.0000000000002372
PMID:36914953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10538912/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1b6/10538912/0213a156420e/cm9-136-2392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1b6/10538912/0213a156420e/cm9-136-2392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1b6/10538912/0213a156420e/cm9-136-2392-g001.jpg

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Dexmedetomidine Attenuated Neuron Death, Cognitive Decline, and Anxiety-Like Behavior by Inhibiting CXCL2 in CA1 Region of AD Mice.右美托咪定通过抑制 AD 小鼠 CA1 区的 CXCL2 减轻神经元死亡、认知下降和焦虑样行为。
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