射频消融与立体定向体部放射治疗肝细胞癌的比较：一项荟萃回归分析。
Radiofrequency ablation versus stereotactic body radiation therapy for hepatocellular carcinoma: a meta-regression.
机构信息
Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
出版信息
Future Oncol. 2023 Feb;19(4):279-287. doi: 10.2217/fon-2022-0893. Epub 2023 Mar 14.
The aim of this meta-regression was to assess the impact of mean/median age, mean/median tumor size, percentage of males in total sample, and total sample size on the comparative effectiveness of radiofrequency ablation (RFA) and stereotactic body radiation therapy (SBRT). Ten studies reporting on the composite outcome of overall survival and local control were included. A significant relationship was found between age and overall survival at 1 and 2 for both RFA and SBRT. A significant relationship was noted also between age and local control at 1 and 2 years for RFA. Patients treated with SBRT had a wider range of tumor sizes and larger tumor sizes; no relationship was observed between tumor size and overall survival or local control by SBRT.
本荟萃回归分析旨在评估平均/中位数年龄、平均/中位数肿瘤大小、总样本中男性比例和总样本量对射频消融（RFA）和立体定向体部放疗（SBRT）的比较效果的影响。共纳入了 10 项报告总生存率和局部控制综合结果的研究。RFA 和 SBRT 的 1 年和 2 年总生存率与年龄呈显著相关。RFA 的 1 年和 2 年局部控制率也与年龄呈显著相关。接受 SBRT 治疗的患者肿瘤大小范围较宽，且肿瘤较大；SBRT 的肿瘤大小与总生存率或局部控制率之间未观察到相关性。
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