织工突变小鼠行为障碍的神经解剖学基础 - Suppr

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Neuroanatomical substrate of behavioural impairment in weaver mutant mice.

作者信息

Triarhou L C, Ghetti B

机构信息

Department of Pathology, Indiana University School of Medicine, Indianapolis 46223.

出版信息

Exp Brain Res. 1987;68(2):434-6. doi: 10.1007/BF00248810.

DOI:10.1007/BF00248810

PMID:3691714

Abstract

摘要

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Selective loss of monoaminergic neurons in weaver mutant mice--an immunocytochemical study.织工突变小鼠单胺能神经元的选择性缺失——一项免疫细胞化学研究。

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Diverse cell death pathways result from a single missense mutation in weaver mouse.在韦弗小鼠中，单个错义突变导致了多种细胞死亡途径。

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Distribution of glutamate receptors of the NMDA subtype in brains of heterozygous and homozygous weaver mutant mice.

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Distribution of dopamine, its metabolites, and D1 and D2 receptors in heterozygous and homozygous weaver mutant mice.杂合和纯合韦弗突变小鼠中多巴胺及其代谢产物以及D1和D2受体的分布

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Amelioration of the behavioral phenotype in weaver mutant mice through bilateral intrastriatal grafting of fetal dopamine cells.

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Topographic distribution of dopamine uptake, choline uptake, choline acetyltransferase, and GABA uptake in the striata of weaver mutant mice.

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本文引用的文献

An analysis of feeding and sensorimotor abilities of rats after decortication.去皮质大鼠进食与感觉运动能力的分析

J Comp Physiol Psychol. 1981 Feb;95(1):85-103. doi: 10.1037/h0077760.

Dopamine deficiency in the weaver mutant mouse.织工突变小鼠中的多巴胺缺乏

J Neurosci. 1982 Mar;2(3):376-80. doi: 10.1523/JNEUROSCI.02-03-00376.1982.

Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum.韦弗突变对边缘和非边缘纹状体中含多巴胺的神经支配有不同影响。

Nature. 1984;307(5946):62-6. doi: 10.1038/307062a0.

Dissociation of the contributions of the prefrontal, motor, and parietal cortex to the control of movement in the rat: an experimental review.大鼠前额叶、运动和顶叶皮质对运动控制贡献的分离：一项实验综述。

Can J Psychol. 1983 Jun;37(2):211-32. doi: 10.1037/h0080724.

Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse.纯合织工突变小鼠小脑中的伯格曼纤维与颗粒细胞迁移

Brain Res. 1974 Sep 13;77(3):484-91. doi: 10.1016/0006-8993(74)90636-2.

Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice.导致韦弗突变小鼠小脑皮质颗粒细胞缺失的发育异常序列。

J Comp Neurol. 1973 Nov 15;152(2):103-32. doi: 10.1002/cne.901520202.

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues.大鼠体内多巴胺的耗竭、刺激或阻断会破坏依赖信标或远处线索的空间导航和运动。

Behav Brain Res. 1985 Oct-Nov;18(1):11-29. doi: 10.1016/0166-4328(85)90165-2.

Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions.织工基因在含多巴胺的神经系统中的表达呈剂量依赖性，且会影响纹状体和非纹状体区域。

J Neurosci. 1986 Nov;6(11):3319-30. doi: 10.1523/JNEUROSCI.06-11-03319.1986.

Motor abnormalities in staggerer mutant mice.蹒跚突变小鼠的运动异常

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Motor abnormalities in weaver mutant mice.

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