Zhang Yifan, Fan Yunge, Ma Zijuan, Wang Dongfang, Fan Fang
School of Psychology, Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China; Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, South China Normal University, Guangzhou, China.
School of Psychology, Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China; Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, South China Normal University, Guangzhou, China.
Sleep Med. 2023 Apr;104:98-104. doi: 10.1016/j.sleep.2023.02.024. Epub 2023 Mar 2.
This study aimed to evaluate the associations of social jetlag and insomnia symptoms with depressive symptoms among adolescents.
A total of 37,871 junior high students completed an online survey between May 24th and Jun 5th, 2022. Insomnia symptoms were assessed by three items based on the Diagnostic and Statistical Manual of Mental Disorders criteria. Social jetlag and depressive symptoms were evaluated by the Munich Chronotype Questionnaire and the Patient Health Questionnaire, respectively. Restricted cubic splines were used to explore the relationship between social jetlag and depressive symptoms. Joint effects of social jetlag and insomnia symptoms on depressive symptoms were estimated using additive interaction models.
The prevalence of depressive symptoms was 13.1%. Depressive symptoms were more common in adolescents with social jetlag ≥2 h (OR: 1.51, 95% CI: 1.39-1.65) and insomnia symptoms (OR: 6.91, 95% CI: 6.41-7.44). There was a J-shaped relationship between social jetlag and depressive symptoms when we took social jetlag as a continuous variable. Moreover, a positive additive interaction of social jetlag ≥2 h and insomnia symptoms on depressive symptoms was found in female adolescents (RERI: 2.30, 95% CI: 0.11-4.49).
Our findings suggested that social jetlag ≥2 h and insomnia are related to the occurrence of depressive symptoms in adolescents. Their coexistence additively enhances the strength of the association with depressive symptoms. Early screening and intervention for insomnia, as well as methods to reduce social jetlag, should be comprised as part of preventive strategies for depression in adolescents.
本研究旨在评估青少年的社会时差和失眠症状与抑郁症状之间的关联。
共有37871名初中生在2022年5月24日至6月5日期间完成了一项在线调查。根据《精神疾病诊断与统计手册》标准,通过三个项目评估失眠症状。分别使用慕尼黑昼夜节律问卷和患者健康问卷评估社会时差和抑郁症状。采用受限立方样条来探索社会时差与抑郁症状之间的关系。使用相加交互作用模型估计社会时差和失眠症状对抑郁症状的联合效应。
抑郁症状的患病率为13.1%。社会时差≥2小时(比值比:1.51,95%置信区间:1.39 - 1.65)和有失眠症状的青少年中抑郁症状更常见(比值比:6.91,95%置信区间:6.41 - 7.44)。当我们将社会时差作为连续变量时,社会时差与抑郁症状之间呈J形关系。此外,在女性青少年中发现社会时差≥2小时和失眠症状对抑郁症状有正向相加交互作用(相对超额危险度增量:2.30,95%置信区间:0.11 - 4.49)。
我们的研究结果表明,社会时差≥2小时和失眠与青少年抑郁症状的发生有关。它们的共存会相加增强与抑郁症状的关联强度。对失眠进行早期筛查和干预以及减少社会时差的方法,应作为青少年抑郁症预防策略的一部分。