阿尔茨海默病中的人格特质和障碍。
Personality traits and disorders in Alzheimer's disease.
机构信息
Faculdade de Psicologia, Universidade de Lisboa, Alameda da Universidade, Lisboa, Portugal.
CICPSI, Faculdade de Psicologia, Universidade de Lisboa, Alameda da Universidade, Lisboa, Portugal.
出版信息
Brain Behav. 2023 Apr;13(4):e2938. doi: 10.1002/brb3.2938. Epub 2023 Mar 14.
BACKGROUND
The relationships between axis II personality disorders and the normative personality traits were explored in the context of current and pre-morbid personality assessment in Alzheimer's disease (AD).
METHODS
The study was conducted with four groups who were administered the NEO-FFI and the PDQ-4+, in the form of individual interview sessions. Current personality measure: consisting of 44 female participants (AD group) and, the control group, consisting of 80 female participants from the population at large. Pre-morbid personality measure: AD group informants (n = 40); control group informants (n = 42).
RESULTS
The results are in line with the literature review and provide new research data. By factorial discriminant analysis, the current and pre-morbid personality variables that differentiate AD from control groups are identified. The personality traits variables are the best discriminators such as low agreeableness, low openness to experience, and high neuroticism, suggesting that the maladaptive personality functioning can be described extending the range of psychopathology to a dimensional approach.
CONCLUSIONS
The study of personality variables seems to suggest, in their inclusion, the possibility to increase sensitivity toward an assessment in AD.
背景
本研究旨在探讨阿尔茨海默病（AD）患者当前和发病前的人格评估背景下，轴 II 型人格障碍与正常人格特质之间的关系。
方法
本研究共纳入 4 组参与者，分别进行了 NEO-FFI 和 PDQ-4+测试，采用个体访谈的形式进行。当前人格评估：包括 44 名女性 AD 患者（AD 组）和 80 名来自普通人群的女性（对照组）。发病前人格评估：AD 组的知情人（n=40）；对照组的知情人（n=42）。
结果
研究结果与文献综述一致，并提供了新的研究数据。通过因子判别分析，确定了区分 AD 组和对照组的当前和发病前的人格变量。人格特质变量是最佳的判别因素，如低宜人性、低开放性和高神经质，这表明适应不良的人格功能可以通过扩展到多维方法的精神病理学范围来描述。
结论
人格变量的研究似乎表明，在 AD 的评估中纳入这些变量可能会提高敏感性。
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