Department of Urology, Yale School of Medicine, New Haven, CT, USA.
Department of Urology, University of California Irvine, Orange, CA, USA.
BJU Int. 2023 Jul;132(1):109-111. doi: 10.1111/bju.16007. Epub 2023 Mar 29.
To outline our step-by-step surgical technique for a transurethral ventral buccal mucosa graft inlay urethroplasty to treat fossa navicularis and distal urethral strictures.
The transurethral ventral inlay urethroplasty is accomplished in four steps. First, after obtaining proper exposure the cicatrice is excised via a transurethral ventral urethrotomy until the lumen is at least 24fr. Second, double arm 6-0 polydioxanone suture is used to deliver the triangular buccal mucosal graft to the proximal extent of the urethrotomy and secured externally. Third, the graft is secured to the meatus with 5-0 polyglactin sutures and additional 6-0 double arm polydioxanone sutures are used to quilt the graft for spread fixation. Finally, a 16fr silicone catheter is placed. Patients are discharged the same day and return for void trial after one week. A retrospective, single institution review was conducted to include all patients who underwent this procedure with a minimum of 1 year follow-up. Patients were analyzed for recurrences, and pre- and post-operative urine flow rates, post void residuals, and patient questionnaires were also reviewed.
44 patients met our inclusion criteria. Median surgical time was 120 minutes. At a mean follow up of 36 months (IQR 22-50) 95% of patients are patent without additional interventions. The 2 patients that did have stricture recurrence were found to have urethral stenosis that extended more proximally, and both were successfully treated with a dorsal onlay buccal urethroplasty. There were significant improvements in urine flow rate, post void residuals, international prostate symptom score and quality of life scores post operatively. There was no difference in post operative sexual function scores.
This minimally invasive transurethral ventral urethroplasty has excellent intermediate term outcomes in terms of traditional objective measures of urethroplasty success and patient reported outcomes.
概述经尿道尿道腹侧颊黏膜镶嵌移植尿道成形术治疗舟状窝和远端尿道狭窄的分步手术技术。
经尿道腹侧镶嵌尿道成形术分四步完成。首先,在获得适当暴露后,通过经尿道腹侧尿道切开术切除瘢痕,直到管腔至少为 24fr。其次,使用双股 6-0 聚二氧杂环已酮缝线将三角形颊黏膜移植物递送至尿道切开术的近端,并在外部固定。第三,用 5-0 聚甘醇酸缝线将移植物固定至尿道口,并用额外的 6-0 双股聚二氧杂环已酮缝线将移植物缝合以进行扩散固定。最后,放置 16fr 硅胶导管。患者当天出院,一周后返回进行排尿试验。对所有接受该手术并随访至少 1 年的患者进行回顾性单机构回顾。分析患者的复发情况,并回顾术前和术后尿流率、剩余尿和患者问卷。
44 例患者符合我们的纳入标准。中位手术时间为 120 分钟。在平均 36 个月(IQR 22-50)的随访中,95%的患者无需进一步干预即可保持通畅。2 例发生吻合口狭窄复发的患者发现尿道狭窄延伸至更近端,均成功接受背侧覆盖颊黏膜尿道成形术治疗。术后尿流率、剩余尿、国际前列腺症状评分和生活质量评分均显著改善,术后性功能评分无差异。
这种微创经尿道尿道腹侧成形术在传统的尿道成形术成功的客观指标和患者报告的结果方面具有优异的中期结果。