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介入治疗在难治性慢性腰痛管理中的应用:45 例前瞻性研究。

Interventional pathway in the management of refractory chronic flank pain: Prospective series in 45 patients.

机构信息

Department of Pain Medicine, Clinical Research Unit in Pain Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.

出版信息

Pain Pract. 2023 Jul;23(6):689-694. doi: 10.1111/papr.13223. Epub 2023 Mar 20.

Abstract

BACKGROUND

Chronic flank pain can pose a therapeutic challenge. Current management centres on visceral pathology affecting the renal system. Acute exacerbations can be severe, requiring emergency admission. Patients usually have well-established visceral pathology including polycystic kidney disease, Fowler's syndrome, and renal calculi disease that often cause recurrent urinary tract infections. However, in many cases, despite negative investigations including imaging, biochemistry and urine analysis, flank pain persists. Abdominal myofascial pain syndrome is a poorly recognized pathology in this cohort. The report describes the underlying pathophysiology and a novel interventional management pathway for patients presenting with refractory flank pain secondary to abdominal myofascial pain syndrome.

METHODS

Adult patients with refractory chronic flank pain at a tertiary renal unit were included as a part of an on-going prospective longitudinal audit. Patients refractory to standard management were offered the interventional pathway. The pathway included two interventions: quadratus lumborum block with steroid and pulsed radio frequency treatment. Patients completed brief pain inventory and hospital anxiety and depression scale questionnaires at baseline, 3 and 6 months postprocedure. Outcomes collected included ability to maintain employment, change in opioid consumption at 6 months and impact on emergency hospital admissions at 12 months after initiation of the pathway.

RESULTS

Forty-five patients were referred to the pain medicine clinic over a seven-year period between 2014 and 2021. All patients were offered the interventions. Four patients refused due to needle phobia. Forty-one patients received transmuscular quadratus lumborum plane block with steroids. Twenty-seven patients (27/41, 66%) reported durable benefit at 6 months and six patients (6/41, 15%) had clinically significant relief at 3 months. Fifteen patients received pulsed radiofrequency to quadratus lumborum plane and 11 patients (73%) reported > 50% analgesia at 6 months. Treatment failure rate was 10% (4/41). Opioid consumption at 6 months and emergency admission at 12 months were reduced post intervention.

CONCLUSION

Abdominal myofascial pain syndrome is a poorly recognized cause of chronic flank pain syndrome. The interventional management pathway could be an effective solution in this cohort.

摘要

背景

慢性腰痛可能是一个治疗上的挑战。目前的治疗主要集中在影响肾脏系统的内脏病变上。急性发作可能很严重,需要紧急入院。患者通常有明确的内脏病变,包括多囊肾病、福勒综合征和肾结石病,这些疾病常导致反复尿路感染。然而,在许多情况下,尽管进行了包括影像学、生物化学和尿液分析在内的阴性检查,腰痛仍持续存在。腹直肌筋膜疼痛综合征是这一人群中一种认识不足的病理。本报告描述了这种情况下的潜在病理生理学,并提出了一种新的介入治疗方法,用于治疗因腹直肌筋膜疼痛综合征导致的难治性腰痛患者。

方法

将在三级肾脏科就诊的难治性慢性腰痛的成年患者纳入正在进行的前瞻性纵向审计的一部分。对标准治疗无效的患者提供介入治疗途径。该途径包括两种干预措施: quadratus lumborum 阻滞加类固醇和脉冲射频治疗。患者在基线、3 个月和 6 个月后完成简短疼痛量表和医院焦虑抑郁量表问卷。收集的结果包括维持就业的能力、6 个月时阿片类药物消耗的变化以及介入治疗开始后 12 个月急诊入院的影响。

结果

在 2014 年至 2021 年的 7 年期间,有 45 名患者被转介到疼痛医学诊所。所有患者均接受了干预措施。由于害怕针,有 4 名患者拒绝。41 名患者接受了 quadratus lumborum 平面肌内阻滞加类固醇。27 名患者(27/41,66%)在 6 个月时有持久的受益,6 名患者(6/41,15%)在 3 个月时有显著缓解。15 名患者接受了 quadratus lumborum 平面脉冲射频治疗,其中 11 名患者(73%)在 6 个月时疼痛减轻超过 50%。治疗失败率为 10%(4/41)。介入治疗后,6 个月时阿片类药物的消耗和 12 个月时急诊入院的次数减少。

结论

腹直肌筋膜疼痛综合征是慢性腰痛综合征的一种认识不足的原因。介入治疗途径可能是该人群的有效解决方案。

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