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对于采用皮质类固醇注射保守治疗的原发性盂肱关节骨关节炎和肩袖关节病患者,影响其进行全肩关节置换术时间的因素。

Factors impacting time to total shoulder arthroplasty among patients with primary glenohumeral osteoarthritis and rotator cuff arthropathy managed conservatively with corticosteroid injections.

作者信息

Shankar Dhruv S, Mojica Edward S, Colasanti Christopher A, Blaeser Anna M, Ortega Paola F, Gonzalez-Lomas Guillem, Jazrawi Laith M

机构信息

Department of Orthopedic Surgery, New York University Langone Health, New York, NY, USA.

出版信息

Clin Shoulder Elb. 2023 Mar;26(1):32-40. doi: 10.5397/cise.2022.01130. Epub 2023 Feb 23.

Abstract

BACKGROUND

The purpose of this study was to identify predictors of the time from initial presentation to total shoulder arthroplasty (TSA) in patients with primary glenohumeral osteoarthritis (OA) and rotator cuff (RTC) arthropathy who were conservatively managed with corticosteroid injections.

METHODS

We conducted a retrospective cohort study of patients who underwent TSA from 2010 to 2021. Kaplan-Meier survival analysis was used to estimate median time to TSA for primary OA and RTC arthropathy patients. The Cox proportional hazards model was used to identify significant predictors of time to TSA and to calculate hazard ratios (HRs) with 95% confidence intervals (CIs). Statistical significance was set at P<0.05.

RESULTS

The cohort included 160 patients with primary OA and 92 with RTC arthropathy. In the primary OA group, median time to TSA was 15 months. Significant predictors of shorter time to TSA were older age at presentation (HR, 1.02; 95% CI, 1.00-1.04; P=0.03) and presence of moderate or severe acromioclavicular joint arthritis (HR, 1.45; 95% CI, 1.05-2.01; P=0.03). In the RTC arthropathy group, median time to TSA was 14 months, and increased number of corticosteroid injections was associated with longer time to TSA (HR, 0.87; 95% CI, 0.80-0.95; P=0.003).

CONCLUSIONS

There are distinct prognostic factors for progression to TSA between primary OA patients and RTC arthropathy patients managed with corticosteroid injections. Multiple corticosteroid injections are associated with delayed time to TSA in RTC arthropathy patients.

摘要

背景

本研究的目的是确定在接受皮质类固醇注射保守治疗的原发性盂肱关节骨关节炎(OA)和肩袖(RTC)关节病患者中,从初次就诊到全肩关节置换术(TSA)的时间预测因素。

方法

我们对2010年至2021年接受TSA的患者进行了一项回顾性队列研究。采用Kaplan-Meier生存分析来估计原发性OA和RTC关节病患者至TSA的中位时间。使用Cox比例风险模型来确定至TSA时间的显著预测因素,并计算95%置信区间(CI)的风险比(HR)。统计学显著性设定为P<0.05。

结果

该队列包括160例原发性OA患者和92例RTC关节病患者。在原发性OA组中,至TSA的中位时间为15个月。至TSA时间较短的显著预测因素为就诊时年龄较大(HR,1.02;95%CI,1.00-1.04;P=0.03)以及存在中度或重度肩锁关节关节炎(HR,1.45;95%CI,1.05-2.01;P=0.03)。在RTC关节病组中,至TSA的中位时间为14个月,皮质类固醇注射次数增加与至TSA时间延长相关(HR,0.87;95%CI,0.80-0.95;P=0.003)。

结论

在接受皮质类固醇注射治疗的原发性OA患者和RTC关节病患者中,进展至TSA存在不同的预后因素。多次皮质类固醇注射与RTC关节病患者至TSA的时间延迟相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/674c/10030987/42c235ad4b24/cise-2022-01130f1.jpg

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