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超越安全保障:探讨情绪为中心的问题解决治疗对降低老年人自杀风险的附加益处,该治疗联合安全计划一同实施。

Beyond maintaining safety: Examining the benefit of emotion-centered problem solving therapy added to safety planning for reducing late life suicide risk.

机构信息

Sierra Pacific Mental Illness Research Education and Clinical Center (MIRECC), Veterans Affairs Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305-5717, USA.

Sierra Pacific Mental Illness Research Education and Clinical Center (MIRECC), Veterans Affairs Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA.

出版信息

Contemp Clin Trials. 2023 May;128:107147. doi: 10.1016/j.cct.2023.107147. Epub 2023 Mar 14.

DOI:10.1016/j.cct.2023.107147
PMID:36921689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10164054/
Abstract

Few clinical trials have examined brief non-pharmacological treatments for reducing suicide risk in older Veterans, a high-risk group. Problem Solving Therapy (PST) is a promising psychosocial intervention for reducing late life suicide risk by increasing adaptive coping to problems through effective problem solving and related coping skills. The current randomized clinical trial will compare the efficacy of six telephone-delivered sessions of Safety Planning (enhanced usual care; EUC) only or an updated version of PST (emotion-centered PST [EC-PST]) + EUC to determine the added clinical benefit of EC-PST for reducing severity of suicidal ideation and for increasing reasons for living, a critical protective factor. Participants randomized to EC-PST + EUC or EUC only will be 150 Veterans (75 each) with active suicidal ideation who are aged 60 or older; have a current DSM-5 anxiety, depressive, and/or trauma-related disorder; and without significant cognitive impairment. Primary outcomes (Geriatric Suicide Ideation Scale and Reasons for Living-Older Adults scale) will be assessed at 11 timepoints: baseline, after each of 6 treatment sessions, posttreatment, and at follow-up at 1, 3, and 6 months posttreatment, and analyzed using mixed effects modeling. Additionally, moderators and mediators of primary outcomes will be examined-functional disability, executive dysfunction, and problem-solving ability. Qualitative feedback from participants will identify potential Veteran-centric changes to the EC-PST protocol and to EUC. Ultimately, the goal of this study is to inform the evidence-based clinical practice guidelines for treatments to reduce suicide risk in older Veterans and specifically to inform clinical decision-making regarding the merit of adding EC-PST to EUC.

摘要

很少有临床试验研究过简短的非药物治疗方法,以降低老年退伍军人这一高风险群体的自杀风险。问题解决疗法(PST)是一种有前途的心理社会干预方法,通过有效解决问题和相关应对技巧,增加适应性应对方式,从而降低晚年自杀风险。目前的随机临床试验将比较六次电话传递的安全计划(增强常规护理;EUC)或经过更新的 PST 版本(以情绪为中心的 PST [EC-PST])+EUC 的疗效,以确定 EC-PST 对降低自杀意念严重程度和增加生活理由(一个关键的保护因素)的附加临床益处。随机分配到 EC-PST+EUC 或仅 EUC 的参与者将是 150 名有自杀意念的退伍军人(各 75 名),年龄在 60 岁或以上;目前患有 DSM-5 焦虑、抑郁和/或创伤相关障碍;且无明显认知障碍。主要结局(老年自杀意念量表和老年人生活理由量表)将在 11 个时间点进行评估:基线、6 次治疗后的每次治疗、治疗后以及治疗后 1、3 和 6 个月的随访,使用混合效应模型进行分析。此外,还将检查主要结局的调节因素和中介因素——功能障碍、执行功能障碍和解决问题的能力。参与者的定性反馈将确定 EC-PST 方案和 EUC 的潜在退伍军人为中心的改变。最终,本研究的目标是为减少老年退伍军人自杀风险的治疗方法提供循证临床实践指南,并特别为在 EUC 中添加 EC-PST 的优点提供临床决策依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b54/10164054/61ad94f80c31/nihms-1885843-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b54/10164054/61ad94f80c31/nihms-1885843-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b54/10164054/61ad94f80c31/nihms-1885843-f0001.jpg

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