Surabhi Divya Meher, Wilson Joseph Charles, Singh Manmeet, Green Lauren
College of Medicine, University of Illinois at Chicago, 1835 W Polk St, Chicago IL 60612 USA.
Department of Radiology, The University of Chicago, 5841 South Maryland Ave MC2026, Chicago, IL 60637 USA.
Radiol Case Rep. 2023 Mar 3;18(5):1788-1792. doi: 10.1016/j.radcr.2023.01.052. eCollection 2023 May.
Invasive breast carcinoma of no special type (IBC-NST) with medullary pattern is an uncommon histologic type of invasive breast carcinoma. It is associated with high-grade, poorly differentiated tumor cells that form large sheets of irregular confluent tumor cells associated with a prominent lymphocytic infiltrate. Patients with IBC-NST with medullary pattern are often postmenopausal women with a high body mass index and multiparity. We report the case of a 71-year-old woman who presented for routine screening mammography and breast mass suspicious for malignancy, initially thought to be invasive ductal carcinoma with an associated prominent lymphoid infiltrate. However, it was ultimately diagnosed as IBC-NST with medullary pattern, and radiologic imaging (particularly ultrasound and mammography) along with pathology review were critical in making the diagnosis. We make the case of the importance of radiographic imaging in diagnosing this condition, as the prognosis of IBC-NST with medullary pattern is typically more favorable compared to IBC-NST.
具有髓样特征的非特殊类型浸润性乳腺癌（IBC-NST）是一种罕见的浸润性乳腺癌组织学类型。它与高级别、低分化的肿瘤细胞相关，这些肿瘤细胞形成大片不规则融合的肿瘤细胞，并伴有显著的淋巴细胞浸润。具有髓样特征的IBC-NST患者通常是绝经后女性，身体质量指数较高且多产。我们报告了一例71岁女性的病例，该患者因常规筛查乳腺钼靶检查发现乳腺肿物且怀疑为恶性，最初被认为是伴有显著淋巴样浸润的浸润性导管癌。然而，最终诊断为具有髓样特征的IBC-NST，放射学成像（尤其是超声和乳腺钼靶检查）以及病理复查对于做出诊断至关重要。我们通过该病例说明了放射学成像在诊断这种疾病中的重要性，因为与IBC-NST相比，具有髓样特征的IBC-NST的预后通常更有利。
