Sharma Anshul, Dwivedi Ankur
Department of Nuclear Medicine, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India.
Department of Radiodiagnosis, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India.
World J Nucl Med. 2022 Oct 28;22(1):40-42. doi: 10.1055/s-0042-1757281. eCollection 2023 Mar.
A 42-year-old male patient with high-risk prostate adenocarcinoma underwent baseline Tc-methylene diphosphonate skeletal scintigraphy, which revealed two skeletal metastases and an area of faint radiotracer uptake in the left femoral shaft. In view of oligo-metastatic nature of the disease in the bone scan and the young age of the patient, he was a candidate for metastases-directed treatment. Single photon emission computed tomography (SPECT)/CT was performed to further characterize this lesion. It was revealed to be a small soft tissue density lesion within the fatty bone marrow density, suggesting bone marrow involvement. A more sensitive evaluation of such areas with faint radiotracer uptake may be needed in high-risk prostate cancer patients where access to advanced modalities is limited. Their significance will also need reassessment as their detection will improve with technological advancements.
一名42岁的高危前列腺腺癌男性患者接受了基线锝-亚甲基二膦酸盐骨闪烁显像，结果显示有两处骨转移以及左股骨干处有一放射性示踪剂摄取微弱的区域。鉴于骨扫描显示疾病为寡转移性质且患者年轻，他适合接受转移灶导向治疗。进行了单光子发射计算机断层扫描（SPECT）/CT以进一步明确该病变特征。结果显示其为脂肪骨髓密度内的一个小软组织密度病变，提示骨髓受累。在获取先进检查手段受限的高危前列腺癌患者中，可能需要对这类放射性示踪剂摄取微弱的区域进行更敏感的评估。随着技术进步其检出率提高，它们的意义也需要重新评估。
