Breast Unit, Champalimaud Clinical Centre, Champalimaud Foundation, Lisbon, Portugal; Surgical Oncology Department, "Prof. Dr. Ion Chiricuta" Institute of Oncology, Cluj-Napoca, Romania; Surgical Oncology and Gynecologic Oncology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Breast Unit, Champalimaud Clinical Centre, Champalimaud Foundation, Lisbon, Portugal; Hospital CUF Cascais, Cascais, Portugal.
Breast. 2023 Jun;69:265-273. doi: 10.1016/j.breast.2023.03.006. Epub 2023 Mar 13.
Simple breast conservation surgery (sBCS) has technically advanced onto oncoplastic breast procedures (OBP) to avoid mastectomy and improve breast cancer patients' psychosocial well-being and cosmetic outcome. Although OBP are time-consuming and expensive, we are witnessing an increase in their use, even for cases that could be managed with sBCS. The choice between keeping it simple or opting for more complex oncoplastic procedures is difficult. This review proposes a pragmatic approach in assisting this decision. Medical literature suggests that OBP and sBCS might be similar regarding local recurrence and overall survival, and patients seem to have higher satisfaction levels with the aesthetic outcome of OBP when compared to sBCS. However, the lack of comprehensive high-quality research assessing their safety, efficacy, and patient-reported outcomes hinders these supposed conclusions. Postoperative complications after OBP may delay the initiation of adjuvant RT. In addition, precise displacement of the breast volume is not effectively recorded despite surgical clips placement, making accurate dose delivery tricky for radiation oncologists, and WBRT preferable to APBI in complex OBP cases. With a critical eye on financial toxicity, patient satisfaction, and oncological outcomes, OBP must be carefully integrated into clinical practice. The thoughtful provision of informed consent is essential for decision-making between sBCS and OBP. As we look into the future, machine learning and artificial intelligence can potentially help patients and doctors avoid postoperative regrets by setting realistic aesthetic expectations.
单纯保乳手术(sBCS)在技术上已经发展为肿瘤整形乳房手术(OBP),以避免乳房切除术,并改善乳腺癌患者的社会心理幸福感和美容效果。尽管 OBP 耗时且昂贵,但我们看到其使用率在增加,即使对于可以通过 sBCS 治疗的病例也是如此。在保持简单与选择更复杂的肿瘤整形手术之间做出选择是困难的。这篇综述提出了一种实用的方法来协助做出这一决策。医学文献表明,OBP 和 sBCS 在局部复发和总生存率方面可能相似,并且与 sBCS 相比,患者对 OBP 的美容效果似乎有更高的满意度。然而,缺乏全面的高质量研究来评估它们的安全性、疗效和患者报告的结果,这限制了这些假设结论的确立。OBP 后的术后并发症可能会延迟辅助放疗的开始。此外,尽管放置了手术夹,但乳房体积的精确移位仍无法有效记录,这使得放射肿瘤学家难以准确输送剂量,并且在复杂的 OBP 病例中,WBRT 优于 APBI。考虑到财务毒性、患者满意度和肿瘤学结果,OBP 必须谨慎地纳入临床实践。在 sBCS 和 OBP 之间做出决策时,仔细提供知情同意至关重要。随着我们展望未来,机器学习和人工智能有可能通过设定现实的审美期望来帮助患者和医生避免术后遗憾。