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Int J Surg Case Rep. 2023 Apr;105:107959. doi: 10.1016/j.ijscr.2023.107959. Epub 2023 Mar 4.
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The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2018 声明:更新共识手术病例报告(SCARE)指南。
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Multiple pregnancies with complete mole and coexisting normal fetus in North and South America: A retrospective multicenter cohort and literature review.北美和南美完全性葡萄胎伴共存正常胎儿的多胎妊娠:回顾性多中心队列研究和文献复习。
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[Twin pregnancy involving a molar pregnancy and living fetus with progression to invasive mole: about two cases].[双胎妊娠,其中一胎为葡萄胎另一胎为活胎,进展为侵袭性葡萄胎:两例报告]
Pan Afr Med J. 2015 Sep 10;22:24. doi: 10.11604/pamj.2015.22.24.7150. eCollection 2015.
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[Twin pregnancy with complete hydatiform mole and coexistent fetus: Report of 4 cases and review of literature].[双胎妊娠合并完全性葡萄胎及共存胎儿:4例报告并文献复习]
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[Twin pregnancy with both complete hydatiform mole and coexistent alive fetus: report of a non-antenatal diagnosed case].[双胎妊娠合并完全性葡萄胎及存活胎儿:1例非产前诊断病例报告]
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Twin pregnancy with complete hydatidiform mole and coexistent fetus: obstetrical and oncological outcomes in a series of 14 cases.双胎妊娠合并完全性葡萄胎及共存胎儿:14例系列病例的产科和肿瘤学结局
Eur J Obstet Gynecol Reprod Biol. 2009 Apr;143(2):84-7. doi: 10.1016/j.ejogrb.2008.12.006. Epub 2009 Feb 3.
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Prenatal diagnosis and management of twin pregnancies complicated by a co-existing molar pregnancy.双胎妊娠合并葡萄胎的产前诊断与管理
Prenat Diagn. 2005 Sep;25(9):772-6. doi: 10.1002/pd.1272.
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Outcome of twin pregnancies with complete hydatidiform mole and healthy co-twin.双胎妊娠中一个为完全性葡萄胎而另一个为健康胎儿的结局
Lancet. 2002 Jun 22;359(9324):2165-6. doi: 10.1016/S0140-6736(02)09085-2.
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Hydatiform mole with coexisting live fetus in dichorionic twin gestation.双绒毛膜双胎妊娠中并存活胎的葡萄胎
Eur J Obstet Gynecol Reprod Biol. 2001 Feb;94(2):301-3. doi: 10.1016/s0301-2115(00)00338-9.
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Hydatidiform mole coexistent with a twin live fetus: a national collaborative study in Japan.葡萄胎与存活双胎胎儿并存:日本一项全国性合作研究
Hum Reprod. 2000 Mar;15(3):608-11. doi: 10.1093/humrep/15.3.608.

双胎妊娠合并完全性葡萄胎与健康胎儿:病例报告及文献复习

Twin pregnancy combining complete hydatidiform mole and healthy fetus: Case report and review of the literature.

作者信息

Khalloufi Chadia, Joudar Imane, El Abbassi Imane, Jalal Mohammed, Lamrissi Amine, Bouhya Said

机构信息

Maternity, University Hospital Abderrahim Harouchi, Casablanca, Morocco; Faculty of Medicine and Pharmacy, University Hassan II, Ain chock BP 5366, 20000 Casablanca, Morocco.

Maternity, University Hospital Abderrahim Harouchi, Casablanca, Morocco; Faculty of Medicine and Pharmacy, University Hassan II, Ain chock BP 5366, 20000 Casablanca, Morocco.

出版信息

Int J Surg Case Rep. 2023 Apr;105:107959. doi: 10.1016/j.ijscr.2023.107959. Epub 2023 Mar 4.

DOI:10.1016/j.ijscr.2023.107959
PMID:36924602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10112189/
Abstract

INTRODUCTION AND IMPORTANCE

Twin pregnancy combining a complete mole and a normal fetal pregnancy with its own healthy trophoblast is a rare entity. A partial molar pregnancy almost always ends in miscarriage due to a triploid fetus.

CASE PRESENTATION

We report the case of a 43-year-old female patient admitted for bleeding during the 20th week of pregnancy. Pelvic ultrasound showed the combination of a complete hydatidiform mole and a normal fetal pregnancy. The decision to medically terminate the pregnancy was taken after consultation with the family. Examination of the placenta and histological study confirmed the diagnosis of complete hydatidiform mole associated with a normal fetus. The evolution was uneventful.

CLINICAL DISCUSSION

Twin pregnancy combining a complete mole and a normal fetal pregnancy with its own healthy trophoblast is a rare entity that should not be misdiagnosed. There is still no consensus in terms of therapeutic attitude, the dilemma remains and the decision should always include the couple after a thorough explanation of all the risks.

CONCLUSION

Our case reaffirms that to successfully manage this rare yet life-threatening condition, heterotopic pregnancy should be included in the differential diagnosis for any gravid women presenting with persistent abdominal pain, abnormal bleeding and/or extrauterine mass.

摘要

引言与重要性

双胎妊娠合并完全性葡萄胎及具有自身健康滋养层的正常胎儿妊娠是一种罕见情况。部分性葡萄胎几乎总是因三倍体胎儿而以流产告终。

病例报告

我们报告一例43岁女性患者,在妊娠第20周时因出血入院。盆腔超声显示完全性葡萄胎与正常胎儿妊娠并存。在与家属协商后决定进行药物性终止妊娠。对胎盘进行检查及组织学研究证实诊断为完全性葡萄胎合并正常胎儿。病情进展平稳。

临床讨论

双胎妊娠合并完全性葡萄胎及具有自身健康滋养层的正常胎儿妊娠是一种罕见情况,不应误诊。在治疗态度方面仍未达成共识,困境依然存在,在充分解释所有风险后,决策应始终包括夫妇双方。

结论

我们的病例再次证实,为成功处理这种罕见但危及生命的情况,对于任何出现持续性腹痛、异常出血和/或宫外肿块的孕妇,应将异位妊娠纳入鉴别诊断。