Silva-Figueroa Angelica M
Universidad Finis Terrae, School of Medicine, Chile; Service of Surgery, Department of Head and Neck Surgery, Hospital Barros Luco Trudeau, Santiago, Chile.
Surg Oncol Clin N Am. 2023 Apr;32(2):251-269. doi: 10.1016/j.soc.2022.10.003.
Parathyroid carcinoma (PC) is a rare endocrine malignancy with an increased incidence in the last decade. There is no reliable prognostic staging system for PC. Several hosts, tumors, and tumor microenvironment factors have been negatively correlated with survival in the last decade. Surgical resection with negative margins is still the standard of treatment in PC. Chemo and radiotherapy have no proven beneficial effect. A new promising approach with molecular profiling could lead to adjuvant therapies.
甲状旁腺癌（PC）是一种罕见的内分泌恶性肿瘤，在过去十年中发病率有所上升。目前尚无可靠的PC预后分期系统。在过去十年中，一些宿主、肿瘤及肿瘤微环境因素与生存率呈负相关。切缘阴性的手术切除仍是PC的标准治疗方法。化疗和放疗尚未证实有有益效果。一种基于分子图谱的新的有前景的方法可能会带来辅助治疗。
