浆液性脉络膜脱离及巩膜炎与坏死性脉络膜肿瘤相关
Serous Choroidal Detachment and Scleritis Associated with Necrotic Choroidal Tumors.
作者信息
Ebert Jared J, Di Nicola Maura, Hansen Eric D, Collon Sean M, Hagen Matthew C, Williams Basil K
机构信息
Ocular Oncology Service, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Ocular Oncology Service, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
出版信息
Ocul Oncol Pathol. 2023 Feb;8(4-6):191-196. doi: 10.1159/000527880. Epub 2022 Nov 4.
PURPOSE
The aim of the study was to describe choroidal detachments and concurrent scleritis associated with necrotic choroidal metastasis or melanoma.
METHODS
We conducted a retrospective case series.
RESULTS
We report 4 patients with scleritis and choroidal detachment with an underlying malignant choroidal tumor. All patients underwent fine-needle aspiration biopsy for cytopathologic characterization of their choroidal tumor, and they all demonstrated evidence of tumor necrosis. Two patients were diagnosed with choroidal metastasis from lung and esophageal adenocarcinoma. Both patients ultimately expired from systemic metastasis. The remaining 2 patients were diagnosed with choroidal melanoma and were successfully treated with plaque radiotherapy.
CONCLUSION
Choroidal detachment with concurrent scleritis can occur as a rare sequelae of tumor necrosis of an underlying choroidal malignancy.
目的
本研究旨在描述与坏死性脉络膜转移瘤或黑色素瘤相关的脉络膜脱离和并发巩膜炎。
方法
我们进行了一项回顾性病例系列研究。
结果
我们报告了4例患有巩膜炎和脉络膜脱离且伴有潜在恶性脉络膜肿瘤的患者。所有患者均接受了细针穿刺活检以对其脉络膜肿瘤进行细胞病理学特征分析，且均显示出肿瘤坏死的证据。2例患者被诊断为肺和食管腺癌的脉络膜转移。这两名患者最终均因全身转移而死亡。其余2例患者被诊断为脉络膜黑色素瘤，并成功接受了敷贴放射治疗。
结论
并发巩膜炎的脉络膜脱离可能是潜在脉络膜恶性肿瘤肿瘤坏死的一种罕见后遗症。
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