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非典型皮肤结核,具有不同寻常的病程。

Atypical cutaneous tuberculosis with an unusual course.

机构信息

Department of Dermatology and Venerology, Ibn Sina Hospital, Mohammed V University in Rabat, Rabat, Morocco.

Department of Anatomopathology, Ibn Sina Hospital, Mohammed V University in Rabat, Rabat, Morocco.

出版信息

Int J Mycobacteriol. 2023 Jan-Mar;12(1):103-106. doi: 10.4103/ijmy.ijmy_4_23.

Abstract

Cutaneous tuberculosis represents the fifth extrapulmonary form in Morocco after pleural, lymph node, urogenital, and intestinal tuberculosis. It is recognized to form a continuous immunopathologic spectrum, ranging from a high intensity to a low intensity of cell-mediated immunity, which explains the multiplicity and heterogeneity of anatomo-clinical forms. Association of multiple forms in the same patient is really rare. In this regard, we report a case of scrofuloderma on axillary tuberculosis adenitis associated to a lupus vulgaris in an immunocompetent patient, which was confirmed by histology, QuantiFERON-TB Gold test, and polymerase chain reaction. He received an antituberculous therapy with clinical regression of the lesions. In conclusion, cutaneous tuberculosis is still endemic in developing countries.The diagnosis is difficult because of its clinical polymorphism. That's why it's should be suspected clinically in the presence of any destructive or verrucous skin lesion evolving without healing for a long period and confirmed by bacteriological examinations and histology.

摘要

皮肤结核是摩洛哥继胸膜、淋巴结、泌尿生殖和肠道结核之后的第五种肺外形式。它被认为形成了一个连续的免疫病理谱,从细胞介导免疫的高强度到低强度,这解释了解剖学和临床形式的多样性和异质性。同一患者的多种形式的联合确实很少见。在这方面,我们报告了一例腋窝结核性淋巴结炎引起的狼疮性皮肤硬结病,该病例通过组织学、QuantiFERON-TB Gold 试验和聚合酶链反应得到证实。他接受了抗结核治疗,病变临床消退。总之,皮肤结核在发展中国家仍然流行。由于其临床表现的多样性,诊断很困难。因此,在存在任何破坏性或疣状皮肤病变且长期不愈合的情况下,应根据临床怀疑进行诊断,并通过细菌学检查和组织学证实。

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