Ngangk Yira Institute for Change, Murdoch University, Murdoch, WA, Australia.
Telethon Kids Institute, The University of Western Australia, Nedlands, WA, Australia.
Aust N Z J Psychiatry. 2023 Oct;57(10):1331-1342. doi: 10.1177/00048674231160986. Epub 2023 Mar 16.
Maternal mental disorders have been associated with adverse perinatal outcomes such as low birthweight and preterm birth, although these links have been examined rarely among Australian Aboriginal populations. We aimed to evaluate the association between maternal mental disorders and adverse perinatal outcomes among Aboriginal births.
We used whole population-based linked data to conduct a retrospective cohort study ( = 38,592) using all Western Australia singleton Aboriginal births (1990-2015). Maternal mental disorders were identified based on the International Classification of Diseases diagnoses and grouped into six broad diagnostic categories. The perinatal outcomes evaluated were preterm birth, small for gestational age, perinatal death, major congenital anomalies, foetal distress, low birthweight and 5-minute Apgar score. We employed log-binomial/-Poisson models to calculate risk ratios and 95% confidence intervals.
After adjustment for sociodemographic factors and pre-existing medical conditions, having a maternal mental disorder in the five years before the birth was associated with adverse perinatal outcomes, with risk ratios (95% confidence intervals) ranging from 1.26 [1.17, 1.36] for foetal distress to 2.00 [1.87, 2.15] for low birthweight. We found similar associations for each maternal mental illness category and neonatal outcomes, with slightly stronger associations when maternal mental illnesses were reported within 1 year rather than 5 years before birth and for substance use disorder.
This large population-based study demonstrated an increased risk of several adverse birth outcomes among Aboriginal women with mental disorders. Holistic perinatal care, treatment and support for women with mental disorders may reduce the burden of adverse birth outcomes.
母体精神障碍与不良围产结局相关,如低出生体重和早产,尽管这些关联在澳大利亚原住民人群中很少被研究。我们旨在评估原住民分娩中母体精神障碍与不良围产结局的关系。
我们使用全人群基于链接的数据进行了一项回顾性队列研究( = 38592),纳入了所有西澳大利亚州的单胎原住民分娩(1990-2015 年)。母体精神障碍是根据国际疾病分类诊断确定的,并分为六大诊断类别。评估的围产结局包括早产、小于胎龄儿、围产儿死亡、重大先天畸形、胎儿窘迫、低出生体重和 5 分钟 Apgar 评分。我们采用对数二项式/Poisson 模型计算风险比和 95%置信区间。
在校正社会人口因素和预先存在的医疗状况后,分娩前五年患有母体精神障碍与不良围产结局相关,风险比(95%置信区间)范围从胎儿窘迫的 1.26(1.17,1.36)到低出生体重的 2.00(1.87,2.15)。我们发现每个母体精神疾病类别和新生儿结局都有类似的关联,当母体精神疾病在分娩前 1 年而不是 5 年报告时,以及当报告物质使用障碍时,关联更为强烈。
这项大型基于人群的研究表明,患有精神障碍的原住民妇女发生多种不良分娩结局的风险增加。对患有精神障碍的妇女进行整体围产期护理、治疗和支持可能会降低不良分娩结局的负担。