Chérrez-Ojeda Iván, Robles-Velasco Karla, Osorio María F, Mejía-Leiva Daniel, Chérrez Annia, Chérrez Sofía, Bernstein Jonathan A, Sarfraz Zouina, Félix Miguel
Universidad Espíritu Santo, Samborondón, Ecuador.
Respiralab Research Group, Guayaquil, Ecuador.
Rev Alerg Mex. 2022 Jun 30;69(1):61-64. doi: 10.29262/ram.v69i1.973.
To assess cutaneous reactions after Pfizer-BioNTech COVID-19 vaccine administration.
A cross-sectional observational study was carried out in health workers belonging to the city of Guayaquil-Ecuador, from March to May 2021. The participants were contacted through a local registry established by the Universidad Espíritu Santo. Frequencies and percentages were used to represent the proportions of nominal variables, while the mean and standard deviation were used for continuous data, given a normal sample distribution.
Local skin reactions were the most frequent, and included redness, edema, and itching. On the other hand, delayed large local skin reactions (generalized rash and pruritus, angioedema, urticaria, eczema, petechiae) were rare and occurred in less than 1.4% of participants, (95% CI = 0.69-1.00). Finally, we did not find cases of anaphylaxis or other life-threatening reactions requiring urgent attention after vaccination.
Our findings suggest that local skin reactions occur in a minority of recipients and are often mild and self-limited.
评估接种辉瑞 - 生物科技公司的新冠疫苗后的皮肤反应。
2021年3月至5月，在厄瓜多尔瓜亚基尔市的医护人员中开展了一项横断面观察性研究。通过圣埃斯皮里图大学建立的当地登记册联系参与者。对于名义变量的比例，用频率和百分比表示；对于服从正态样本分布的连续数据，用均值和标准差表示。
局部皮肤反应最为常见，包括发红、水肿和瘙痒。另一方面，延迟性的大面积局部皮肤反应（全身性皮疹和瘙痒、血管性水肿、荨麻疹、湿疹、瘀点）很少见，不到1.4%的参与者出现此类反应（95%置信区间 = 0.69 - 1.00）。最后，我们未发现接种疫苗后发生过敏反应或其他需要紧急处理的危及生命反应的病例。
我们的研究结果表明，局部皮肤反应在少数接种者中出现，且通常症状轻微、具有自限性。
