成帽或形成：形成蛋白和加帽蛋白竞争纤维末端来塑造肌动蛋白网络。
Cappin' or formin': Formin and capping protein competition for filament ends shapes actin networks.
机构信息
Department of Cell and Developmental Biology, SUNY Upstate Medical University , Syracuse, NY, USA.
出版信息
J Cell Biol. 2023 Apr 3;222(4). doi: 10.1083/jcb.202302009. Epub 2023 Mar 16.
Abstract
How cells assemble distinct actin networks from shared cytoplasmic components remains an important unresolved question. In this issue, Wirshing et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202209105) demonstrate how capping protein and formin competition for actin filament barbed ends controls the assembly of branched and linear actin networks.
摘要
细胞如何从共享的细胞质成分中组装出不同的肌动蛋白网络，这仍然是一个重要的未解决的问题。在本期杂志中，Wirshing 等人（2023. J. Cell Biol. https://doi.org/10.1083/jcb.202209105）展示了盖帽蛋白和形成蛋白如何通过竞争肌动蛋白丝的突环末端来控制分支和线性肌动蛋白网络的组装。
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