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[伴有指甲改变的疣状表皮发育不良样遗传性皮肤病]

[Epidermodysplasia verruciformis-like genodermatosis with changes in the nails].

作者信息

Salamon T, Halepović E, Berberović L, Nikulin A, Lazović-Tepavac O, Cerkez A, Basić V

机构信息

Lehrstuhl für Dermatologie und Venerologie, Medizinischen Fakultät, Universität Banja Luka.

出版信息

Hautarzt. 1987 Sep;38(9):525-31.

PMID:3692854
Abstract

Nine cases of genodermatosis are described, in which the clinical symptoms and light-microscope findings resembled those in epidermodysplasia verruciformis (Lewandowsky-Lutz disease). All had alterations of the fingernails and toenails. Viruses were not found in a excised skin lesions or in the fingernail clipping from the patients. The mode of inheritance of the dermatosis seems to be X-chromosomal and dominant. It is the opinion of the authors that this dermatosis is separate entity from epidermodysplasia verruciformis.

摘要

本文描述了9例遗传性皮肤病患者,其临床症状和光学显微镜检查结果与疣状表皮发育不良(Lewandowsky-Lutz病)相似。所有患者均有指甲和趾甲改变。在切除的皮肤病变组织或患者的指甲剪屑中均未发现病毒。该皮肤病的遗传方式似乎为X染色体显性遗传。作者认为,这种皮肤病是一种有别于疣状表皮发育不良的独立疾病。

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