癫痫急救治疗：比较已批准和常用苯二氮䓬类药物制剂。
Seizure Rescue Therapies: Comparing Approved and Commonly Used Benzodiazepine Formulations.
机构信息
School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Department of Internal Medicine, University Teaching Hospital, Lusaka, Zambia.
出版信息
Neurotherapeutics. 2023 Apr;20(3):758-766. doi: 10.1007/s13311-023-01359-3. Epub 2023 Mar 16.
Abstract
Acute seizure therapies given out of the hospital are important for interrupting acute repetitive and prolonged seizures and preventing hospitalization. These vary in their administration routes, indications for children and adults, pharmacologic profiles, and efficacy. We reviewed and compared the uses of current formulations available to treat acute seizures, including newly released intranasal (IN) benzodiazepines and older formulations which are widely used for interrupting seizures.
摘要
院外急性癫痫治疗对于中断急性反复性和持续性癫痫发作以及预防住院非常重要。这些治疗方法在给药途径、儿童和成人的适应证、药物特性和疗效方面有所不同。我们回顾并比较了目前可用于治疗急性癫痫的各种制剂的用途，包括新推出的鼻内（IN）苯二氮䓬类药物和广泛用于中断癫痫发作的旧制剂。
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