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通过喷雾干燥法将橄榄叶提取物中的活性成分保存在可生物降解聚合物中:优化、体外胃肠道消化及应用

Preservation of active components in olive leaf extract by spray drying method in biodegradable polymers: Optimization, in vitro gastrointestinal digestion and application.

作者信息

Toprakçı İrem, Cosgun Gulderen, Balci-Torun Ferhan, Torun Mehmet, Şahin Selin

机构信息

Faculty of Engineering, Chemical Engineering Department, Istanbul University-Cerrahpasa, Istanbul, Türkiye.

Faculty of Engineering, Food Engineering Department, Akdeniz University, Antalya, Türkiye.

出版信息

Phytochem Anal. 2024 Dec;35(8):1757-1770. doi: 10.1002/pca.3222. Epub 2023 Mar 17.

Abstract

INTRODUCTION

Encapsulation of the bioactive ingredients in biodegradable and edible polymers is an alternative novel application method to keep these kind of natural products stable.

OBJECTIVE

The purpose is to optimize the encapsulation system of olive leaf extract by spray drying method, and to apply the products into a model food.

METHODS

Olive leaf extract was encapsulated in arabic gum/maltodextrin blend by spray drying method. Combined design approach under I-optimal design type was used to optimize the system. Characterisation studies under moisture content, water activity, solubility, bulk density, tapped density, Carr index, particle size distribution, powder morphology and glass transition temperature were applied to the microparticles obtained under optimum conditions. The bioavailability of the encapsulated active material was tested by in vitro gastrointestinal digestion. Furthermore, microparticles produced under optimum conditions were also evaluated for a potential functional food application.

RESULTS

The optimum conditions were achieved by arabic gum/maltodextrin (3.7:6.3) with 10% (w/v) in the mixture of wall material and active material under 165.5°C to achieve maximum encapsulation efficiency (86.92%), encapsulation yield (71.32%) and antioxidant activity (5.74 mg Trolox equivalent antioxidant capacity/g dry microparticle).

CONCLUSIONS

Olive leaf extract encapsulated in arabic gum/maltodextrin may be a good alternative additive to prevent the lipid oxidation in fat-containing food products as well as improvement of the product quality by functional properties.

摘要

引言

将生物活性成分包裹于可生物降解的可食用聚合物中是一种使这类天然产品保持稳定的新型替代应用方法。

目的

旨在通过喷雾干燥法优化橄榄叶提取物的包封系统,并将所得产品应用于一种模拟食品。

方法

采用喷雾干燥法将橄榄叶提取物包裹于阿拉伯胶/麦芽糊精混合物中。运用I-最优设计类型下的组合设计方法优化该系统。对在最佳条件下获得的微粒进行水分含量、水分活度、溶解度、堆积密度、振实密度、卡尔指数、粒度分布、粉末形态及玻璃化转变温度等表征研究。通过体外胃肠道消化试验测试包封活性物质的生物利用度。此外,还对在最佳条件下制备的微粒在潜在功能性食品应用方面进行了评估。

结果

在壁材与活性物质混合物中,阿拉伯胶/麦芽糊精比例为3.7:6.3、浓度为10%(w/v),于165.5°C条件下实现了最佳条件,可达到最大包封效率(86.92%)、包封产率(71.32%)及抗氧化活性(5.74毫克特洛克斯当量抗氧化能力/克干燥微粒)。

结论

包裹于阿拉伯胶/麦芽糊精中的橄榄叶提取物可能是一种很好的替代添加剂,可防止含脂肪食品中的脂质氧化,并通过功能特性提高产品质量。

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