科兴新冠疫苗不影响卵巢储备功能。

CoronaVac vaccine does not affect ovarian reserve.

作者信息

Şenkaya Ayşe Rabia, Çil Zafer, Keskin Ömür, Güneş Mehmet Emin, Can Öztekin Deniz

机构信息

Gynecology and Obstetrics Clinic, İzmir Bakırçay University Çiğli Training and Research Hospital, Turkey.

Biochemistry, İzmir Bakırçay University Çiğli Training and Research Hospital, Turkey.

出版信息

Ginekol Pol. 2023;94(4):298-302. doi: 10.5603/GP.a2023.0025. Epub 2023 Mar 17.

DOI:10.5603/GP.a2023.0025

PMID:36929802

Abstract

OBJECTIVES

In this study, our aim is to investigate the effect of CoronaVac vaccine on ovarian reserve in female patients followed up for infertility.

MATERIAL AND METHODS

Our study is a retrospective study. Forty-six infertile patients who received two doses of CoronaVac vaccine one month apart and had not had a previous Covid 19 infection were included in the study. Anti-müllerian hormone (AMH) and folliculometry of 46 patients one month before CoronaVac vaccine and one month after the second dose of vaccine were compared.

RESULTS

There was no statistically significant difference in the change of AMH level and follicle number before and after vaccination (respectively p = 0.366; 0.610).

CONCLUSIONS

Considering that having a COVID-19 infection has a negative effect on female fertility and causing ovarian damage in recent studies, vaccination is a rational and cost-effective approach to protect ovarian reserve. Knowing that the vaccine does not have a negative effect on fertility may increase the application of the vaccine in women of reproductive age.

摘要