Department of Neurology, Shijiazhuang People's Hospital, Hebei, China.
Department of Neurology, Guiyang First People's Hospital, Guizhou, China.
Medicine (Baltimore). 2023 Mar 17;102(11):e33263. doi: 10.1097/MD.0000000000033263.
Bilateral facial palsy (BFP) has been identified as a possible neurological complication of human immunodeficiency virus (HIV) infection, but only a limited number of cases have been reported in the literature. The purpose of this study was to deepen our understanding of the etiology of BFP. Case report: We report the case of a 46-year-old married bisexual man with BFP associated with HIV infection. The patient underwent serological testing for HIV and was positive. In the absence of any other evidence of underlying systemic disease, facial palsy is thought to be secondary to HIV infection. After antiretroviral therapy, the patient recovered completely from facial palsy within 3 months. Results: HIV infection often involves BFP. The pathophysiology of this clinical presentation is thought to be related to the immune response to the systemic transmission of the virus. Conclusions: Most patients with BFP have underlying systemic causes, particularly autoimmune diseases. The exclusion of HIV infection in patients with BFP is essential for the early diagnosis and management of HIV.
双侧面瘫（Bilateral facial palsy，BFP）已被确定为人类免疫缺陷病毒（human immunodeficiency virus，HIV）感染的一种可能的神经并发症，但文献中仅报道了有限数量的病例。本研究旨在深入了解 BFP 的病因。
我们报告了一例 46 岁的已婚双性恋男性，患有与 HIV 感染相关的双侧面瘫。患者接受了 HIV 的血清学检测，结果呈阳性。由于没有任何其他潜在系统性疾病的证据，面瘫被认为是 HIV 感染的继发表现。在接受抗逆转录病毒治疗后，患者在 3 个月内完全从面瘫中恢复。
HIV 感染常累及 BFP。这种临床表现的病理生理学被认为与病毒全身传播引起的免疫反应有关。
大多数 BFP 患者存在潜在的系统性病因，特别是自身免疫性疾病。在 BFP 患者中排除 HIV 感染对于 HIV 的早期诊断和管理至关重要。
