Department of Perinatology, University of Health Sciences, Etlik Zubeyde Hanim Women's Health Training and Research Hospital, Ankara, Turkey.
Eur Rev Med Pharmacol Sci. 2023 Mar;27(5):1971-1979. doi: 10.26355/eurrev_202303_31561.
There is no study that compares the diagnostic performance of ATV and ESV techniques in detecting cleft palate. We aimed to evaluate the diagnostic accuracy of two ultrasound techniques: axial-transverse (ATV) and "equal sign" view (ESV), in detecting fetal cleft palate without cleft lip.
This prospective study was conducted from March 2019 to January 2022 in a tertiary referral hospital. Secondary palates were assessed with ATV and ESV by two experienced fetal medicine specialists who were blinded to each other's ultrasound findings. Final diagnosis was done according to postnatal physical examination. The sensitivity and specificity of the two techniques were calculated.
A total of 311 pregnancies which met the study criteria were evaluated. Postnatal physical examination showed that 13 (0.4%) neonates had cleft palate only (CPO). According to final diagnosis the sensitivity, specificity, positive predictive value and negative predictive value for ATV were 100%, 98.7%, 76.4%, 100% and 100% for ESV were 76.9%, 97.8%, 58.9% and 99%, respectively.
ATV in 2D ultrasound provides higher sensitivity and specificity than ESV in detecting CPO.
目前尚无研究比较 ATV 和 ESV 技术在检测腭裂中的诊断性能。我们旨在评估两种超声技术——轴向-横向（ATV）和“等号”视图（ESV）——在检测无唇裂的胎儿腭裂中的诊断准确性。
这是一项前瞻性研究，于 2019 年 3 月至 2022 年 1 月在一家三级转诊医院进行。由两位具有丰富经验的胎儿医学专家使用 ATV 和 ESV 评估二级腭，这两位专家彼此之间的超声检查结果均为盲法。最终诊断依据产后体格检查。计算了两种技术的敏感性和特异性。
共有 311 例符合研究标准的妊娠进行了评估。产后体格检查显示，13 例（0.4%）新生儿仅患有腭裂（CPO）。根据最终诊断，ATV 的敏感性、特异性、阳性预测值和阴性预测值分别为 100%、98.7%、76.4%、100%，ESV 则分别为 76.9%、97.8%、58.9%和 99%。
二维超声中的 ATV 在检测 CPO 方面比 ESV 具有更高的敏感性和特异性。
