兔滑膜年龄相关性变化的超微结构研究

Jilani M, Ghadially F N

Department of Pathology, University Hospital, University of Saskatchewan, Saskatoon, Canada.

J Anat. 1986 Jun;146:201-15.

The synovial membranes of 5 young rabbits about 6 weeks old and 5 older rabbits about 3-4 years old were studied with the light and electron microscopes, with a view to discovering any age-associated changes that might occur. Several age-associated changes were noted. These included: (1) a reduction in the overall population of synovial intimal cells; (2) a statistically significant reduction in type B cells and a relative increase in type A cells; (3) the emergence of atrophic cells poorly endowed with organelles; (4) decreased vascularity; and (5) fibrosis.

对5只约6周龄的幼兔和5只约3 - 4岁的成年兔的滑膜进行了光镜和电镜研究，以发现可能出现的任何与年龄相关的变化。观察到了一些与年龄相关的变化。这些变化包括：（1）滑膜内膜细胞总数减少；（2）B型细胞数量在统计学上显著减少，A型细胞相对增加；（3）出现细胞器较少的萎缩细胞；（4）血管减少；（5）纤维化。