Josephson M E, Horowitz L N
Am J Cardiol. 1979 Mar;43(3):631-42. doi: 10.1016/0002-9149(79)90024-9.
The refinement of the techniques of programmed stimulation and intracardiac recording has led to understanding of the mechanism of ventricular tachycardia and these techniques can be applied clinically to the development of therapeutic regimens. The efficacy of drug therapy can be assessed in sequential studies evaluating the ability of drugs to prevent initiation of the arrhythmia by electrical stimulation. The efficacy of pacemaker therapy can be evaluated by assessing the effects of stimulation during the tachycardia. The recent development of endocardial mapping provides the surgeon with a tool to guide therapeutic surgical ablation of the site of origin of the tachycardia. Such an electrophysiologic approach to recurrent ventricular tachycardia can lead to the rapid development of successful therapy under controlled conditions.
程控刺激和心内记录技术的改进，使人们对室性心动过速的机制有了了解，并且这些技术可在临床上应用于治疗方案的制定。在一系列研究中，通过评估药物预防电刺激诱发心律失常的能力，可以评估药物治疗的疗效。通过评估心动过速期间刺激的效果，可以评估起搏器治疗的疗效。心内膜标测技术的最新发展为外科医生提供了一种工具，用于指导对心动过速起源部位进行治疗性手术消融。这种针对复发性室性心动过速的电生理方法，可在可控条件下促使成功治疗方法的快速发展。
