单囊胚移植周期中第5天低质量囊胚和第6天高质量囊胚的妊娠结局。
The pregnancy outcomes of day-5 poor-quality and day-6 high-quality blastocysts in single blastocyst transfer cycles.
作者信息
Zhang Guang-Li, Sun Tian-Yi, Li Sen, Jiang Man-Xi, Guo Lei
机构信息
Center for Reproductive Medicine, Guangdong Second Provincial General Hospital, Guangzhou, China.
出版信息
Clin Exp Reprod Med. 2023 Mar;50(1):63-68. doi: 10.5653/cerm.2022.05540. Epub 2023 Feb 23.
OBJECTIVE
This study compared the outcomes of single blastocyst transfer cycles, using day- 5 poor-quality blastocysts and day-6 high-quality blastocysts.
METHODS
We analyzed 462 frozen-thawed embryo transfer (FET) cycles performed at our center from January 2014 to December 2019. The cycles were divided into two groups: a day-5 poor-quality blastocyst transfer group (group A) and a day-6 high-quality blastocyst transfer group (group B). The clinical outcomes were tested.
RESULTS
In groups A and B, respectively, the clinical pregnancy rate (CPR; 61.65% vs. 67.17%, p=0.258), implantation rate (IR; 61.65% vs. 67.17%, p=0.258), and live birth rate (LBR; 69.51% vs. 77.83%, p=0.134) showed no significant differences. Moreover, when day-3 embryo quality was considered, the CPR, IR, and LBR were also similar in group A and group B (p>0.05).
CONCLUSION
The clinical outcomes of day-5 poor-quality blastocysts and day-6 high-quality blastocysts were similar, suggesting that the developmental speed of the embryo might be more important than embryo quality for the clinical outcomes of single blastocyst transfer in FET cycles.
目的
本研究比较了使用第5天低质量囊胚和第6天高质量囊胚进行单囊胚移植周期的结局。
方法
我们分析了2014年1月至2019年12月在本中心进行的462个冻融胚胎移植（FET）周期。这些周期被分为两组：第5天低质量囊胚移植组（A组）和第6天高质量囊胚移植组（B组）。对临床结局进行了检测。
结果
A组和B组的临床妊娠率（CPR；61.65%对67.17%，p=0.258）、着床率（IR；61.65%对67.17%，p=0.258）和活产率（LBR；69.51%对77.83%，p=0.134）均无显著差异。此外，当考虑第3天胚胎质量时，A组和B组的CPR、IR和LBR也相似（p>0.05）。
结论
第5天低质量囊胚和第6天高质量囊胚的临床结局相似，这表明在FET周期单囊胚移植的临床结局方面，胚胎的发育速度可能比胚胎质量更重要。
Zotero 插件