Michael Faith, Farrow Jamie, Main Anthony
Northern Ontario School of Medicine University, Sudbury, ON, Canada.
Department of Echocardiography, Health Sciences North, Sudbury, ON, Canada.
Clin Med Insights Case Rep. 2023 Mar 13;16:11795476231160045. doi: 10.1177/11795476231160045. eCollection 2023.
The current literature focuses on the risk of infective endocarditis (IE) transcatheter aortic valve implantation (TAVI). However, the risk of IE in patients for TAVI is not well-studied. We present a unique case of a patient waiting for TAVI with decompensated heart failure who was found to have a large mitral vegetation, and consider risk factors for the development of IE in this population.
We report the case of an 85-year-old male with severe aortic stenosis and recurrent small bowel angiodysplasias, requiring frequent blood transfusions and intravenous iron. He presented to a peripheral hospital in decompensated heart failure. Transfer was arranged to our center to expedite TAVI, under the premise that worsening aortic stenosis precipitated his decompensated state. Prior to TAVI, an echocardiogram was done, and demonstrated a 30 × 18 mm mass on the mitral valve with anterior leaflet perforation and severe mitral regurgitation. The findings were consistent with IE, and the TAVI was cancelled. Despite antibiotic therapy, the patient unfortunately deteriorated and palliative care was provided.
This case highlights the need for further research regarding the risk of IE in patients waiting for TAVI. Current literature focuses on the development and management of IE following TAVI. Clinicians must understand that TAVI candidates have multiple risk factors for IE, including valvular disease, age, and comorbidities. IE should be considered as a possible cause for decompensated heart failure in patients awaiting TAVI.
当前文献聚焦于经导管主动脉瓣植入术(TAVI)后感染性心内膜炎(IE)的风险。然而,TAVI患者发生IE的风险尚未得到充分研究。我们报告了一例等待TAVI且伴有失代偿性心力衰竭的患者,该患者被发现有一个巨大的二尖瓣赘生物,并探讨了该人群发生IE的危险因素。
我们报告了一例85岁男性患者,患有严重主动脉瓣狭窄和复发性小肠血管发育异常,需要频繁输血和静脉补铁。他因失代偿性心力衰竭就诊于一家周边医院。在主动脉瓣狭窄加重导致其失代偿状态的前提下,安排将其转至我们中心以加快TAVI进程。在TAVI之前,进行了超声心动图检查,结果显示二尖瓣上有一个30×18mm的团块,伴有前叶穿孔和严重二尖瓣反流。这些发现与IE相符,TAVI被取消。尽管进行了抗生素治疗,但患者不幸病情恶化,随后提供了姑息治疗。
该病例凸显了对等待TAVI患者发生IE风险进行进一步研究的必要性。当前文献聚焦于TAVI后IE的发生及管理。临床医生必须明白,TAVI候选患者有多种发生IE的危险因素,包括瓣膜疾病、年龄和合并症。对于等待TAVI的患者,IE应被视为失代偿性心力衰竭的一个可能原因。