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癫痫对芬兰儿童因伤住院风险的影响。

Impact of epilepsy on the risk of hospital-treated injuries in Finnish children.

作者信息

Ripatti Liisi, Puustinen Laura, Rautava Päivi, Koivisto Mari, Haataja Leena

机构信息

Department of Pediatric Surgery, Turku University Hospital and University of Turku, Turku, Finland.

Department of Public Health, University of Turku, Turku, Finland.

出版信息

Epilepsy Behav Rep. 2023 Jan 16;21:100587. doi: 10.1016/j.ebr.2023.100587. eCollection 2023.

Abstract

OBJECTIVES

To study the effect of epilepsy on the risk of injury in children.

METHODS

All first-born singleton children (n = 133055) born in 2001 - 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the onset of epilepsy. Four matched controls were chosen for every subject.

RESULTS

Epilepsy had been diagnosed in 0.66 % of children. During follow-up, 12 % of 884 children with epilepsy and 9 % of 3536 controls were hospitalized for injuries (HR 1.387 [95 % CI 1.115 - 1.725];  = 0.0033). Risk for injuries was higher in boys than girls (p = 0.0057). Mean age at the first injury was 6.8 years (SD 3.3, median 7, range 0-13) in subjects and 7.2 years (SD 3.2, median 8, range 1-13) in controls (p = 0.272). The rate of hospitalization did not differ according to the type of epilepsy. The risks of subjects compared to controls were not significantly different concerning the nature of injury or survival.

CONCLUSIONS

Children with epilepsy are at increased risk for hospital-treated injuries. The spectrum of injuries and the risk for death due to injuries are not different in children with and without epilepsy.

摘要

目的

研究癫痫对儿童受伤风险的影响。

方法

纳入2001年至2006年在芬兰出生的所有头胎单胎儿童(n = 133055)。从国家登记处收集数据,直至癫痫发作后五年内首次因伤住院治疗。为每个受试者选择四个匹配的对照组。

结果

0.66%的儿童被诊断患有癫痫。在随访期间,884名癫痫儿童中有12%因伤住院,3536名对照组儿童中有9%因伤住院(风险比1.387 [95%置信区间1.115 - 1.725];P = 0.0033)。男孩受伤的风险高于女孩(P = 0.0057)。受试者首次受伤的平均年龄为6.8岁(标准差3.3,中位数7,范围0 - 13),对照组为7.2岁(标准差

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ee8/10015441/2cebcaf61c85/gr1.jpg

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