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左乙拉西坦肝损伤：一种良性抗癫痫药物？

Levetiracetam Liver Injury: A Benign Antiepileptic Agent?

作者信息

Hegazy Yassmin, Axley Page, Lee Goo, Gray Meagan

机构信息

Department of Medicine, University of Alabama Birmingham Hospital, Birmingham, AL.

Department of Internal Medicine, University of Alabama Birmingham Hospital, Birmingham, AL.

出版信息

ACG Case Rep J. 2023 Mar 16;10(3):e01003. doi: 10.14309/crj.0000000000001003. eCollection 2023 Mar.

DOI:10.14309/crj.0000000000001003
PMID:36936131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10019274/
Abstract

Levetiracetam is a commonly prescribed antiepileptic agent and has rarely been linked to hepatotoxicity. This case describes a patient with drug-induced autoimmune hepatitis secondary to levetiracetam.

摘要

左乙拉西坦是一种常用的抗癫痫药物，很少与肝毒性相关。本病例描述了一名继发于左乙拉西坦的药物性自身免疫性肝炎患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0100/10019274/554cad3fb987/ac9-10-e01003-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0100/10019274/02dedc7b7460/ac9-10-e01003-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0100/10019274/554cad3fb987/ac9-10-e01003-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0100/10019274/02dedc7b7460/ac9-10-e01003-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0100/10019274/554cad3fb987/ac9-10-e01003-g002.jpg

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Asian J Neurosurg. 2019 Jul-Sep;14(3):878-882. doi: 10.4103/ajns.AJNS_246_17.
3
A Rare Case of DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) Syndrome with Cholecystitis in a Patient on Levetiracetam.1例服用左乙拉西坦的患者发生伴胆囊炎的DRESS（药物超敏反应伴嗜酸性粒细胞增多和全身症状）综合征的罕见病例。
Cureus. 2019 Mar 13;11(3):e4245. doi: 10.7759/cureus.4245.
4
Case Report: Levetiracetam causing acute liver failure complicating post-operative management in a neurosurgical patient.病例报告：左乙拉西坦导致急性肝衰竭，使一名神经外科患者的术后管理复杂化。
F1000Res. 2019 Feb 15;8:187. doi: 10.12688/f1000research.18198.1. eCollection 2019.
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