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本文引用的文献

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Clinicopathologic study of 90 cases of trichofolliculoma.90例毛发瘤的临床病理研究
J Eur Acad Dermatol Venereol. 2017 Mar;31(3):e141-e142. doi: 10.1111/jdv.13960. Epub 2016 Sep 18.
2
Dermoscopy of trichofolliculoma: a rare hair follicle hamartoma.毛发滤泡瘤的皮肤镜检查:一种罕见的毛囊错构瘤。
J Eur Acad Dermatol Venereol. 2017 Feb;31(2):e123-e124. doi: 10.1111/jdv.13870. Epub 2016 Aug 9.
3
GATA3 Expression in Normal Skin and in Benign and Malignant Epidermal and Cutaneous Adnexal Neoplasms.GATA3在正常皮肤以及良性和恶性表皮及皮肤附属器肿瘤中的表达
Am J Dermatopathol. 2015 Dec;37(12):885-91. doi: 10.1097/DAD.0000000000000306.
4
Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia.Pygo2 调节β-连环蛋白诱导的毛囊干细胞/祖细胞激活和皮肤过度增生。
Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10215-20. doi: 10.1073/pnas.1311395111. Epub 2014 Jun 30.
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Umbilicated nodule over eyebrow.眉弓处脐凹状结节。
Dermatol Online J. 2013 Sep 14;19(9):19622.
6
Trichofolliculoma: a rare variant of hair follicle hamartoma.毛发滤泡瘤:一种罕见的毛囊错构瘤变体。
Dermatol Online J. 2013 Aug 15;19(8):19264.
7
Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias.抑制 P-钙黏蛋白阳性毛发祖细胞中的 BMP 信号通路会导致类似于毛发滤泡瘤的毛发滤泡肿瘤。
J Biomed Sci. 2011 Dec 14;18(1):92. doi: 10.1186/1423-0127-18-92.
8
Perifollicular nodule on the face of a young man.一名年轻男性面部的毛囊周围结节。
Indian J Dermatol Venereol Leprol. 2011 Jul-Aug;77(4):531-3. doi: 10.4103/0378-6323.82401.
9
A revaluation of trichofolliculoma: the histopathological and immunohistochemical features.毛发毛囊瘤的重新评估:组织病理学和免疫组化特征
Am J Dermatopathol. 2010 Feb;32(1):35-43. doi: 10.1097/DAD.0b013e3181a77414.
10
The histogenesis of nevoid tumors of the skin. The folliculoma--a hair-follicle tumor.皮肤痣样肿瘤的组织发生。毛囊瘤——一种毛囊肿瘤。
Arch Dermatol. 1960 Jun;81:922-30. doi: 10.1001/archderm.1960.03730060038007.

一种罕见的皮肤错构瘤性附属器肿瘤:毛发滤泡瘤。

A Rare Cutaneous Hamartomatous Adnexal Tumor: Trichofolliculoma.

作者信息

Zekey Emre, Kurtipek Gülcan Saylam

机构信息

Dermatology, Sivas Numune Hospital, Sivas, Turkey.

Dermatology, Selcuk University Medical School Hospital, Konya, Turkey.

出版信息

Skin Appendage Disord. 2023 Mar;9(2):121-125. doi: 10.1159/000527981. Epub 2022 Dec 8.

DOI:10.1159/000527981
PMID:36937157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10015648/
Abstract

INTRODUCTION

Trichofolliculoma is a very rare, benign hamartomatous skin adnexal tumor originating from the hair follicle. The tumor which presents as a papule or nodule is usually observed on the scalp and face.

CASE PRESENTATION

We report the case of a 49-year-old female who presented with a solitary papule on the nose. The lesion which was observed macroscopically and dermoscopically compatible with trichofolliculoma was completely removed by punch biopsy. The diagnosis of trichofolliculoma was confirmed histopathologically, and no recurrence was observed in the follow-up.

CONCLUSION

Trichofolliculomas can macroscopically mimic some skin cancers such as basal cell carcinoma and sebaceous carcinoma. Awareness of its typical clinical and dermoscopic features facilitates diagnosis and prevents aggressive surgical intervention.

摘要

引言

毛发滤泡瘤是一种非常罕见的良性错构瘤性皮肤附属器肿瘤,起源于毛囊。该肿瘤表现为丘疹或结节,通常出现在头皮和面部。

病例报告

我们报告一例49岁女性,其鼻部出现一个孤立性丘疹。经肉眼和皮肤镜观察,该病变与毛发滤泡瘤相符,通过打孔活检将其完全切除。经组织病理学确诊为毛发滤泡瘤,随访期间未观察到复发。

结论

毛发滤泡瘤在肉眼上可模仿一些皮肤癌,如基底细胞癌和皮脂腺癌。了解其典型的临床和皮肤镜特征有助于诊断,并可避免激进的手术干预。