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猫抓病性淋巴结炎表现为右上臂和腋窝肿块:一例酷似淋巴瘤的病例报告及潜在的诊断陷阱。

Cat-Scratch Lymphadenitis Presenting with Right Upper Arm and Axillary Masses: a Case Report Mimicking Lymphoma and Potential Diagnostic Pitfall.

机构信息

Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

出版信息

Med Arch. 2022 Dec;76(6):480-483. doi: 10.5455/medarh.2022.76.480-483.

DOI:10.5455/medarh.2022.76.480-483
PMID:36937617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10019884/
Abstract

BACKGROUND

Cat scratch disease (CSD) is an infectious disease caused by a cat's scratch, hard enough to break the skin's surface. Clinical manifestations include inflammatory lymphadenopathy and papular lesions at the site of the injury. However, it may be mistaken for a neoplasm-related process e.g., lymphoma due to its similar clinical presentation.

OBJECTIVE

To report a CSD case in an Indonesian male presenting with mass-like symptoms in the oncologic ward of our center.

CASE REPORT

A 24-year-old male presented with painful and swelling masses in the right upper arm and right armpit for the last 4 months, enlarged progressively, and feverish for two days. Our initial differential diagnosis was lymphoma by history and routine physical examination, however. The patient reported a history of sleeping with his cat and recently experiencing a cat bite. We conducted the ultrasonography and lymph node biopsy to establish the final diagnosis and it was revealed to be related to CSD. The patient was treated with lymphadenectomy and azithromycin 500 mg bd for 7 days. The patient was completely treated with no additional complaints after two weeks of follow-up.

CONCLUSION

The differential diagnosis for CSD is relatively broad, including active infection, an ongoing inflammatory process, or a metastatic process; hence, thorough diagnostic approaches should be made in approaching CSD cases to avoid the pitfall or mistreatment in advance.

摘要

背景

猫抓病(CSD)是一种由猫抓引起的传染病,抓力足以划破皮肤表面。临床表现包括炎症性淋巴结病和损伤部位的丘疹病变。然而,由于其相似的临床表现,它可能被误诊为与肿瘤相关的过程,例如淋巴瘤。

目的

报告一例在我们中心肿瘤科病房出现肿块样症状的印度尼西亚男性 CSD 病例。

病例报告

一名 24 岁男性因右上臂和右腋窝疼痛性肿胀肿块就诊,持续 4 个月,逐渐增大,并发热两天。根据病史和常规体格检查,我们最初的鉴别诊断为淋巴瘤,但患者报告说有与猫一起睡觉的病史,并最近经历了猫咬伤。我们进行了超声检查和淋巴结活检以确定最终诊断,结果显示与 CSD 相关。患者接受了淋巴结切除术和阿奇霉素 500mg bid 治疗 7 天。经过两周的随访,患者完全治愈,无其他不适。

结论

CSD 的鉴别诊断较为广泛,包括活动性感染、持续的炎症过程或转移性过程;因此,在处理 CSD 病例时应进行彻底的诊断方法,以避免事先出现陷阱或治疗不当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/efe9f9431b20/medarch-76-480-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/24f98cae5e63/medarch-76-480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/24005cb1c44e/medarch-76-480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/a76294860f99/medarch-76-480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/efe9f9431b20/medarch-76-480-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/24f98cae5e63/medarch-76-480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/24005cb1c44e/medarch-76-480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/a76294860f99/medarch-76-480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a2/10019884/efe9f9431b20/medarch-76-480-g004.jpg

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本文引用的文献

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Concurrence of cat-scratch disease and paradoxical tuberculosis-IRIS lymphadenopathy: a case report.猫抓病与结核分枝杆菌感染诱导的免疫重建炎症综合征相关性淋巴结病共存:一例报告。
BMC Infect Dis. 2022 Mar 3;22(1):213. doi: 10.1186/s12879-022-07170-3.
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Cat at home? Cat scratch disease with atypical presentations and aggressive radiological findings mimicking sarcoma, a potential diagnostic pitfall.家中的猫?表现不典型且影像学表现具有侵袭性、类似肉瘤的猫抓病,可能导致诊断陷阱。
Acta Orthop. 2021 Dec;92(6):753-759. doi: 10.1080/17453674.2021.1941624. Epub 2021 Jun 24.
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Cat Scratch Disease and Bartonellaceae: The Known, the Unknown and the Curious.
猫抓病和巴尔通体科:已知的、未知的和好奇的。
Pediatr Infect Dis J. 2021 May 1;40(5S):S11-S15. doi: 10.1097/INF.0000000000002776.
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Cat Scratch Disease Is an Entity Often Diagnosed in Breast Imaging Department During Axillary Lymph Node Assessment.猫抓病是一种在腋窝淋巴结评估期间经常在乳腺影像科被诊断出来的病症。
Cureus. 2020 Jul 19;12(7):e9272. doi: 10.7759/cureus.9272.
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Lymphadenitis associated with cat-scratch disease simulating a neoplasm: Imaging findings with histopathological associations.与猫抓病相关的淋巴结炎模拟肿瘤:影像学表现与组织病理学关联
Oncol Lett. 2018 Jan;15(1):195-204. doi: 10.3892/ol.2017.7311. Epub 2017 Oct 31.
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