Forbes Edward, Wulff-Vester Anders Keim, Hvoslef-Eide Trine A K
Department of Plant Sciences, Faculty of Biosciences, Norwegian University of Life Sciences (NMBU), Aas, Norway.
Front Plant Sci. 2023 Mar 1;14:1137598. doi: 10.3389/fpls.2023.1137598. eCollection 2023.
Last decade's advances in biotechnology, with the introduction of CRISPR, have challenged the regulatory framework for competent authorities all over the world. Hence, regulatory issues related to gene editing are currently high on the agenda both in the EU and in the European Economic Area (EEA) Agreement country of Norway, particularly with regards to sustainable agriculture. During the negotiations on the EEA Agreement, Norway was allowed to retain three extra aims in the Gene Technology Act: "That the production and use of GMO happens in an ethical way, is beneficial to society and is in accordance with the principle of sustainable development". We argue the case that taking sustainability into the decisions on regulating gene edited products could be easier in Norway than in the EU because of these extra aims. Late blight is our chosen example, as a devastating disease in potato that is controlled in Norway primarily by high levels of fungicide use. Also, many of these fungicides are being banned due to negative environmental and health effects. The costs of controlling late blight in Norway were calculated in 2006, and since then there have been new cultivars developed, inflation and an outbreak of war in Europe increasing farm input costs. A genetically modified (GM) cisgenic late blight resistant (LBR) potato presents a possible solution that could reduce fungicide use, but this could still be controversial. This paper aims to discuss the advantages and disadvantages of approving the commercial use of a GM LBR potato cultivar in Norway and compare these against currently used late blight management methods and conventional potato resistance breeding. We argue that a possible route for future regulatory framework could build upon the proposal by the Norwegian Biotechnology Advisory Board from 2019, also taking sustainability goals into account. This could favour a positive response from the Competent Authorities without breeching the European Economic Area (EEA) Agreement. Perhaps the EU could adopt a similar approach to fulfil their obligations towards a more sustainable agriculture?
过去十年间,随着CRISPR技术的引入,生物技术取得了诸多进展,这对全球各主管当局的监管框架构成了挑战。因此,与基因编辑相关的监管问题目前在欧盟以及挪威这个欧洲经济区(EEA)协定国的议程上占据重要位置,特别是在可持续农业方面。在关于EEA协定的谈判过程中,挪威被允许在《基因技术法》中保留三个额外目标:“转基因生物的生产和使用要符合道德规范,对社会有益,并符合可持续发展原则”。我们认为,由于这些额外目标,在挪威将可持续性纳入基因编辑产品监管决策可能比在欧盟更容易。晚疫病是我们选择的例子,它是马铃薯的一种毁灭性病害,在挪威主要通过大量使用杀菌剂来控制。此外,由于对环境和健康有负面影响,许多这类杀菌剂正被禁用。2006年计算了挪威控制晚疫病的成本,从那时起,出现了新的品种,通货膨胀以及欧洲爆发战争导致农场投入成本增加。一种转基因(GM)的顺式基因抗晚疫病(LBR)马铃薯提供了一种可能的解决方案,可以减少杀菌剂的使用,但这仍可能存在争议。本文旨在讨论在挪威批准转基因LBR马铃薯品种商业化使用的利弊,并将其与目前使用的晚疫病管理方法以及传统马铃薯抗性育种进行比较。我们认为,未来监管框架的一条可能途径可以基于挪威生物技术咨询委员会2019年的提议,并考虑可持续发展目标。这可能有利于主管当局做出积极回应,同时又不违反欧洲经济区(EEA)协定。或许欧盟可以采取类似方法来履行其在实现更可持续农业方面的义务?